临床误诊误治2025，Vol.38Issue(13)：11-15,5.DOI:10.3969/j.issn.1002-3429.2025.13.003
误诊为硬膜下血肿的颅内B淋巴母细胞淋巴瘤临床剖析
Clinical Analysis of Intracranial B Lymphoblastic Lymphoma Misdiagnosed as Subdural Hematoma
摘要
Abstract
Objective To explore the clinical features,causes of misdiagnosis and preventive measures of intracranial B lymphoblastic lymphoma.Methods The clinical data of a patient with intracranial B lymphoblastic lymphoma who was misdiag-nosed in November 2022 were retrospectively analyzed.Results The patient presented with sudden speech difficulties.After cranial CT examination,it was misdiagnosed as subdural hematoma.After corresponding treatment,there was some improvement.Symptoms occurred multiple times within one month.After re-admission,a plain and enhanced brain MRI scan was performed,which showed an abnormal enhanced shadow under the left frontal and temporal cranial plates.The possibility of a malignant lesion of the dura mater was considered:a malignant meningioma or lymphoma?The patient's family requested a transfer to a higher-level hospital for further treatment.A resection of the intracranial space-occupying lesion was performed at the higher-level hospital,and the pathological examination confirmed it as B lymphoblastic lymphoma.The misdiagnosis lasted one month.After surgical treat-ment,the patient improved and was discharged.Conclusion Intracranial B lymphoblastic lymphoma belongs to primary central nervous system lymphoma(PCNSL),which is a rare extranodal lymphoma.PCNSL may be misdiagnosed in radiology and has similar imaging features to many diseases,including meningiomas,subdural or epidural hematomas.When receiving such patients in clinical practice,if the initial therapeutic effect of the disease is not favorable,intracranial B lymphoblastic lymphoma should be considered and pathological examination should be performed as soon as possible.关键词
B淋巴母细胞淋巴瘤/颅内肿瘤/原发性中枢神经系统淋巴瘤/误诊/硬膜下血肿Key words
B lymphoblastic lymphoma/Intracranial tumors/Primary central nervous system lymphoma/Misdiagno-sis/Subdural hematoma分类
医药卫生引用本文复制引用
张鹏,王志强,刘辉,吕沛东,程夏飞,张俊江,郭世豪,魏海亮..误诊为硬膜下血肿的颅内B淋巴母细胞淋巴瘤临床剖析[J].临床误诊误治,2025,38(13):11-15,5.基金项目
河北省医学适用技术跟踪项目(GZ2023074) （GZ2023074）
