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胃底腺型腺癌的临床病理学特征及分子遗传学进展

谷夏斐 刘键平

临床与实验病理学杂志2025,Vol.41Issue(7):924-928,934,6.
临床与实验病理学杂志2025,Vol.41Issue(7):924-928,934,6.DOI:10.13315/j.cnki.cjcep.2025.07.013

胃底腺型腺癌的临床病理学特征及分子遗传学进展

Clinicopathological features and molecular genetic advances in gastric adenocarci-noma of fundic gland type

谷夏斐 1刘键平1

作者信息

  • 1. 四川大学华西医院病理科,成都 610000
  • 折叠

摘要

Abstract

Gastric adenocarcinoma of fundic gland type(GA-FG)is a newly reported gastric tumor,which is a highly differentiated adenocarcinoma with a better prognosis.It has been included in the 2019 WHO Classification of Digestive Tumors.However,further knowledge is still needed for GA-FG clinically and pathologically.GA-FG is divid-ed into 3 types,including chief cell-predominant,parietal cell-predominant,and mixed cell-predominant.Diagnosis and differential diagnosis mainly rely on pathohistological morphology and immunohistochemistry.This article reviews the clinical features,endoscopy,electron microscopy,histologic morphology,immunohistochemistry,possible molecu-lar mechanisms and prognosis of GA-FG.The aim is to enable clinicians and pathologists to keep abreast of new ad-vances in the disease and to improve diagnosis and treatment.

关键词

胃底腺型腺癌/主细胞/壁细胞/文献综述

Key words

gastric adenocarcinoma of fundic gland type/chief cell/parietal cell/literature review

分类

医药卫生

引用本文复制引用

谷夏斐,刘键平..胃底腺型腺癌的临床病理学特征及分子遗传学进展[J].临床与实验病理学杂志,2025,41(7):924-928,934,6.

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