辽宁大学学报(自然科学版)2025,Vol.52Issue(2):136-144,9.
吸入暴露下毒性相关有害结局路径研究进展
Progress in Toxicity-Related Adverse Outcome Pathways Under Inhalation Exposure Research
邢立国 1张明明 1陈烨2
作者信息
- 1. 辽宁大学药学院,辽宁沈阳 110036||沈阳沈化院测试技术有限公司,辽宁沈阳 110021
- 2. 辽宁大学药学院,辽宁沈阳 110036
- 折叠
摘要
Abstract
In recent years,the frameworks of adverse outcome pathways(AOPs)has entered a rapid growth phase.As an integrative biological knowledge framework,AOPs systematically elucidate inhalation toxicity mechanisms by constructing AOPs networks,providing a scientific basis for the development of alternative testing methods and risk assessment frameworks for novel chemicals.This paper briefly summarizes the research progress of inhalation toxicity-related AOPs,the application of AOPs frameworks in related fields,and the main challenges currently faced in AOPs development,aiming to provide theoretical support and references for further AOPs development and implementation.关键词
有害结局路径(AOPs)/吸入暴露/定量AOPs/定性AOPsKey words
adverse outcome pathways(AOPs)/inhalation exposure/quantitative adverse outcome pathways/qualitative adverse outcome pathways分类
资源环境引用本文复制引用
邢立国,张明明,陈烨..吸入暴露下毒性相关有害结局路径研究进展[J].辽宁大学学报(自然科学版),2025,52(2):136-144,9.