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急性心肌梗死老年患者溶栓抢救失败后机械取栓的影响因素分析

曹燕清 黄敏 苗柳

老年医学与保健2025,Vol.31Issue(3):653-658,6.
老年医学与保健2025,Vol.31Issue(3):653-658,6.

急性心肌梗死老年患者溶栓抢救失败后机械取栓的影响因素分析

Analysis of influencing factors for mechanical thrombectomy after failed thrombolytic rescue in elderly patients with acute my-ocardial infarction

曹燕清 1黄敏 2苗柳3

作者信息

  • 1. 柳州市人民医院健康管理中心,广西柳州 545006
  • 2. 柳州市人民医院放射科介入室,广西柳州 545006
  • 3. 广西医科大学附属柳州市人民医院心血管内科,广西柳州 545006
  • 折叠

摘要

Abstract

Objective To investigate the influencing factors for mechanical thrombectomy after failed thrombolytic res-cue in elderly patients with acute myocardial infarction(AMI),and provide a basis for improving the success rate of patient rescue.Methods The clinical data of 242 elderly AMI patients who underwent thrombolytic rescue therapy in People's Hospi-tal of Liuzhou City between January 2023 and August 2024 were retrospectively analyzed.Their general clinical characteristics,AMI features,blood lipid and blood routine test characteristics were analyzed.A multivariate Logistic regression model was used to identify the influencing factors for mechanical thrombectomy after failed thrombolysis in elderly AMI patients.Results There were statistically significant differences in the rate of mechanical thrombectomy after thrombolysis failure among elderly patients with acute myocardial infarction of different ages,genders,pre-thrombolysis systolic blood pressure,diastolic blood pressure,history of hypertension,time from symptom onset to thrombolysis,pre-thrombolysis platelet distribution width(PDW)and mean platelet volume(MPV)levels(P<0.05).Both univariate and multivariate logistic regression analyses in-dicated that age,history of hypertension,time from symptom onset to thrombolysis,pre-thrombolysis PDW,and pre-thrombol-ysis MPV were all significant influencing factors for mechanical thrombectomy after failed thrombolysis in elderly AMI patients(P<0.05).Conclusion Elderly AMI patients who are older,and have a history of hypertension,a longer time from onset to thrombolysis and higher levels of PDW and MPV before thrombolysis have a higher rate of mechanical thrombectomy after failed thrombolysis rescue.For these high-risk patients,attention should be paid to improving thrombolytic rescue methods to reduce the failure rate of thrombolysis.

关键词

老年/急性心肌梗死/机械取栓/溶栓失败/影响因素

Key words

elderly/acute myocardial infarction/mechanical thrombectomy/thrombolysis failure/influencing factor

引用本文复制引用

曹燕清,黄敏,苗柳..急性心肌梗死老年患者溶栓抢救失败后机械取栓的影响因素分析[J].老年医学与保健,2025,31(3):653-658,6.

老年医学与保健

1008-8296

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