老年医学与保健2025，Vol.31Issue(3)：675-680,6.
老年冠心病患者心电图QTc间期、QRS时限值与疾病严重程度及临床转归的关系研究
Study on relationship between electrocardiogram QTc interval and QRS duration and disease severity and clinical outcomes in elderly patients with coronary heart disease
孔阿丽 1王晓凌 1姜艳1
作者信息
- 1. 绵阳市第一人民医院(绵阳四○四医院)心电图室,四川绵阳 621000
- 折叠
摘要
Abstract
Objective To analyze the relationship of electrocardiogram QTc interval and QRS duration and disease se-verity and clinical outcomes in elderly patients with coronary heart disease(CHD).Methods A retrospective analysis was conducted on 98 elderly CHD patients admitted to First People's Hospital of Mianyang City between January 1,2020,and Oc-tober 31,2024.According to the Gensini disease severity score,they were divided into mild(n=30,Gensini score 0-24),moderate(n=40,Gensini score 25-49),and severe groups(n=28,Gensini score ≥50).In addition,according to the oc-currence of adverse cardiovascular events(MACE),they were divided into MACE group(n=29)and non-MACE group(n=69).Multivariate Logistic regression was used to analyze the relationship between QTc interval and QRS duration and dis-ease severity and clinical outcomes of elderly CHD.The area under the receiver operating characteristic(ROC)curve(AUC)was used to evaluate the value of QTc interval and QRS duration in assessing CHD severity and outcomes of patients.Results The QTc interval and QRS duration in the moderate and severe groups were longer than those in the mild group(P＜0.05).Multivariate analysis suggested that QTc interval and increased QRS duration were independent risk factors for the ag-gravation of CHD(P＜0.05).ROC curve revealed that the AUC of QTc interval combined with QRS duration in evaluating the severity of CHD was 0.888(P＜0.05).The QTc interval and QRS duration in the MACE group were longer than those in the non-MACE group(P＜0.05).Multivariate analysis indicated that prolonged QTc interval and increased QRS duration were independent risk factors for poor clinical outcomes of elderly CHD patients(P＜0.05).ROC curve showed that the AUC of combination of QTc interval and QRS duration in assessing clinical outcomes of the elderly CHD patients was 0.880(P＜0.05).Conclusion The changes of electrocardiogram QTc interval and QRS duration are closely related to disease severity and clinical outcomes of elderly CHD patients.These indicators can be used to evaluate the disease progression and outcomes of elderly CHD patients,so as to provide guidance for clinical treatment.关键词
老年/冠心病/心电图/QTc间期/QRS时限值/疾病严重程度/临床转归Key words
elderly/coronary heart disease/electrocardiogram/QTc interval/QRS duration/disease severity/clinical outcome引用本文复制引用
孔阿丽,王晓凌,姜艳..老年冠心病患者心电图QTc间期、QRS时限值与疾病严重程度及临床转归的关系研究[J].老年医学与保健,2025,31(3):675-680,6.
