护理学报2025，Vol.32Issue(14)：1-6,6.DOI:10.16460/j.issn2097-6569.2025.14.001
鼻咽癌患者放疗相关症状群及其网络分析
Radiotherapy-related symptom clusters in patients with nasopharyngeal carcinoma:a network analysis
摘要
Abstract
Objectives To investigate the prevalence and severity of symptoms in nasopharyngeal carcinoma patients during radio-therapy,to construct a network of radiotherapy-related symptoms for this group of population to identify symptom clusters,core symp-toms and bridge symptom,and to provide reference for precise symptom management.Methods From November 2023 to August 2024,we recruited 210 nasopharyngeal carcinoma patients by using convenience sampling from a tertiary grade-A hospital in Guang-zhou.General Information Questionnaire and Anderson Symptom Assessment Scale Head and Neck Module were used to investigate the patients.Exploratory factor analysis was used to extract symptom clusters.A symptom network based on R packages was construct-ed;centrality indicators and core symptoms and bridge symptoms were analyzed and determined.Results The most common symp-tom of nasopharyngeal carcinoma patients undergoing radiotherapy was oral or pharyngeal mucus(99.5%);The most serious symptom was dry mouth;Four symptom clusters were identified:oropharyngeal symptom cluster,mood sleep symptom cluster,gastrointestinal symptom cluster and nerve-related symptom cluster,which could explain 69.163%of the total variance.In symptom network,difficulty swallowing or chewing had the greatest strength and expected influence(rs=1.400,rE=1.398);fatigue had the greatest closeness and bridge strength(rc=0.004,rbs=0.610).Conclusion Oropharyngeal symptom cluster is the core symptom cluster;difficulty swallowing or chewing is the core symptom,and fatigue is the most important bridge symptom in the symptom group of patients with nasopharyn-geal carcinoma undergoing radiotherapy.Nursing staff can develop individualized interventions for core symptom and bridge symptom to improve the efficiency of symptom management in patients undergoing radiotherapy for nasopharyngeal carcinoma.关键词
鼻咽癌/放疗/核心症状/症状网络/症状管理Key words
nasopharyngeal carcinoma/radiotherapy/core symptom/symptom network/symptom management分类
医药卫生引用本文复制引用
李静,蔡文文,吴庆彩,唐超,曹月尧,宋亚兰..鼻咽癌患者放疗相关症状群及其网络分析[J].护理学报,2025,32(14):1-6,6.基金项目
广东省医学科研基金项目(A2019138) （A2019138）
