南京中医药大学学报2025，Vol.41Issue(7)：847-855,9.DOI:10.14148/j.issn.1672-0482.2025.0847
类器官和器官芯片:中医药现代化的前沿策略
Organoids and Organ-on-Chips:Cutting-Edge Strategies for the Modernization of Chinese Medicine
摘要
Abstract
Although significant progress has been made in the modernization of Chinese medicine,the current challenges,inclu-ding inconsistent diagnostic and treatment standards,complex molecular mechanisms,and insufficient safety evidence,have signifi-cantly restricted its modernization process.Microfluidic technology provides a new solution for Chinese medicine research with its ability to precisely control fluids and construct bionic microenvironments.Organoid and organ-on-a-chip technologies use microfluidic tech-nology as carriers to provide technical support for the visualization of Chinese medicine theory,discovery of pharmacological sub-stances,analysis of action mechanisms,and toxicity evaluation through multi-organ interconnection models.These technological break-throughs provide an innovative platform for analyzing Chinese medicine theory,driving Chinese medicine research from empirical analy-sis to systematic and dynamic simulations,providing crucial technical support for Chinese medicine internationalization and precision medicine transformation.关键词
中医药现代化/微流控技术/类器官和器官芯片/精准医学/中医整体观Key words
modernization of Chinese medicine/microfluidic technology/organoids and organoid-on-chips/precision medicine/holistic philosophy of Chinese medicine分类
医药卫生引用本文复制引用
韩欣,沈培亮,马月美,贾媛媛..类器官和器官芯片:中医药现代化的前沿策略[J].南京中医药大学学报,2025,41(7):847-855,9.基金项目
国家自然科学基金面上项目(32471475,82405137) （32471475,82405137）
南京中医药大学中药制药过程控制与智能制造技术全国重点实验科研创新项目(NZYSKL240201) （NZYSKL240201）
