南京中医药大学学报2025，Vol.41Issue(7)：889-895,7.DOI:10.14148/j.issn.1672-0482.2025.0889
基于脑玄府与胶质淋巴系统的相似性探讨抑郁症的病理机制
Exploring the Pathological Mechanism of Depression Based on the Similarity between the Brain Xuanfu and the Glymphatic System
摘要
Abstract
It is proposed that the brain Xuanfu and the glymphatic system(GS)have commonality in physiological structure and similarity in functions such as transporting brain substances,transmitting brain information and clearing metabolites.It is believed that GS may be the substantial manifestation of the brain Xuanfu,and GS dysfunction is the key pathological link of depression.Xuanfu stagnation and Shenji dysfunction are the core pathogenesis of depression.Taking"Brain Xuanfu-GS"as the starting point,the patho-logical mechanism of depression is deeply explored,providing a theoretical basis for the clinical diagnosis and treatment of depression in traditional Chinese medicine.关键词
抑郁症/胶质淋巴系统/脑玄府/病理机制Key words
depression/glymphatic system/brain Xuanfu/pathological mechanism分类
医药卫生引用本文复制引用
唐红,李惠菁,王丹,李涓,刘小菠,马星怡,李雨谿,金荣疆,刘欢..基于脑玄府与胶质淋巴系统的相似性探讨抑郁症的病理机制[J].南京中医药大学学报,2025,41(7):889-895,7.基金项目
国家自然科学基金面上项目(82374559) （82374559）
国家自然科学基金青年科学基金项目(82305363) （82305363）
四川省自然科学基金项目(2023NSFSC1824) （2023NSFSC1824）
中国博士后科学基金第73批面上资助项目(2023MD734102) （2023MD734102）
四川省中医药管理局项目(2023MS285) （2023MS285）
