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蠕虫感染与宿主肠道菌群互作机制研究进展

许阳 刘怡慧 郭小腊 郭爱疆 张少华 李继东 王帅

农业科学研究2025,Vol.46Issue(2):84-90,7.
农业科学研究2025,Vol.46Issue(2):84-90,7.

蠕虫感染与宿主肠道菌群互作机制研究进展

Research Progress on the Interaction Mechanism Between Worm Infection and Host Gut Microbiota

许阳 1刘怡慧 2郭小腊 2郭爱疆 2张少华 2李继东 3王帅1

作者信息

  • 1. 宁夏大学动物科技学院,宁夏银川 750021||中国农业科学院兰州兽医研究所,甘肃兰州 730000||兰州大学动物医学与生物安全学院/动物疫病防控全国重点实验室,甘肃兰州 730000
  • 2. 中国农业科学院兰州兽医研究所,甘肃兰州 730000
  • 3. 宁夏大学动物科技学院,宁夏银川 750021
  • 折叠

摘要

Abstract

In recent years,increasing body of evidence has been achieved in elucidating the interplay between worm infection and the intestinal microbiota.Worm infections have been demonstrated to modulate the host's intestinal microbiota and regulate the host immune response.Furthermore,changes in the gut microbiota consequent to worm infections can reciprocally influence the parasitic environment of worms,consequently impacting their survival.This bidirectional interaction between worms and gut microbiota results in significant modifications to the host's gut environment,thereby influencing various stages of disease progression.Based on the classification of helminths,in this study,we comprehensively reviewed the regulatory mechanisms underlying the interaction of Nematodes,Cestoda,Trematodes and gut microbiota,as well as their respective roles in modulating the host immune response.Our findings offer valuable insights and serve as a foundation for further research endeavors in related fields.

关键词

蠕虫感染/肠道菌群/免疫反应/免疫调节

Key words

worm infection/gut microbiota/immune response/immune regulation

分类

农业科技

引用本文复制引用

许阳,刘怡慧,郭小腊,郭爱疆,张少华,李继东,王帅..蠕虫感染与宿主肠道菌群互作机制研究进展[J].农业科学研究,2025,46(2):84-90,7.

基金项目

国家重点研发计划项目(2023YFD1801700) (2023YFD1801700)

甘肃省杰出青年基金项目(21JR7RA027) (21JR7RA027)

农业科学研究

1673-0747

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