肿瘤预防与治疗2025，Vol.38Issue(7)：587-592,6.DOI:10.3969/j.issn.1674-0904.2025.07.004
共面与非共面容积旋转调强技术在胸腺肿瘤放射治疗中的剂量学比较
Dosimetric Comparison of Coplanar and Non-coplanar Volumetric Modula-ted Arc Therapy in Radiotherapy for Thymic Tumors
孙斌 1徐程 1杜司续 1钟思瑶 1原静 1高玉艳1
作者信息
- 1. 101100 北京,首都医科大学附属北京潞河医院放疗科
- 折叠
摘要
Abstract
Objective:To compare the dosimetric advantages between coplanar and non-coplanar volumetric modulated arc therapy(VMAT)in treatment of thymic tumors.Methods:Fourteen patients with thymus tumor were randomly enrolled to develop coplanar and non-coplanar VMAT plans,respectively.PTV and dosimetric parameters of organs at risk were com-pared between the two groups,including:target conformity index(CI);dose homogeneity index(HI);V30,V20,V5 of lung exposure ≥30 Gy,20 Gy,5 Gy volume;mean lung dose(MLD)of the whole lung;V40,V30 and the mean exposure dose Dmean of the heart;the minimum dose D1cc within the 1cc volume of maximum exposure of the esophagus and trachea;the maximum exposure dose Dmax of the spinal cord.Paired sample t-test or Wilcoxon rank sum test was used for statistical analy-sis,and P＜0.05 was considered as statistically significant difference.Results:CI and HI of coplanar plan PTV were better than those of non-coplanar plan(P＜0.05).V30 of both lungs in the coplanar plan were better than that in the non-coplanar plan(P＜0.05),while V5 and MLD were higher than those in the non-coplanar plan(P＜0.05).The differences in V20,however,were statistically insignificant(P=0.875).The Dmean of the esophagus in the coplanar plan was significantly lower than that in the non-coplanar plan(P＜0.05),and the monitor units were significantly higher for the coplanar plan(P＜0.05).However,no statistically significant differences were observed between the plans for the V40,V30 and Dmean of the heart,the D1cc of the esophagus,D1cc and Dmean of the trachea and Dmax of the spinal cord(P＞0.05).Conclusion:Non-coplanar plans for thymic tumors have certain advantages in protecting the lungs,heart,and trachea,but the dose to the esophagus is higher.关键词
胸腺肿瘤/容积旋转调强/共面计划/非共面计划Key words
Thymic tumor/Volumetric modulated arc ther-apy/Coplanar plan/Non-coplanar plan分类
医药卫生引用本文复制引用
孙斌,徐程,杜司续,钟思瑶,原静,高玉艳..共面与非共面容积旋转调强技术在胸腺肿瘤放射治疗中的剂量学比较[J].肿瘤预防与治疗,2025,38(7):587-592,6.
