上海预防医学2025，Vol.37Issue(5)：410-415,6.DOI:10.19428/j.cnki.sjpm.2025.24532
2013-2023年上海市浦东新区儿童呼吸道合胞病毒感染特征
Characteristics of respiratory syncytial virus infection in children in Pudong New Area,Shanghai,2013‒2023
摘要
Abstract
[Objective]To investigate the infection characteristics of respiratory syncytial virus(RSV)in children with acute respiratory tract infection(ARI)in Pudong New Area,Shanghai,from 2013 to 2023,so as to provide an evidence for the prevention and control of RSV in Shanghai.[Methods]Children who sought medical care at sentinel healthcare facilities in Pudong New Area,Shanghai,between January 2013 and December 2023 and met the case definition of ARI were included in the study.Nasopharyngeal swab samples were collected and tested for viral pathogens using real-time fluorescene PCR,and the clinical information of whom was collected simultaneously.[Results]A total of 4 980 children were included in the ARI surveillance,among whom 231 tested positive for RSV,with an overall detection rate of 4.64%.Of these,106 cases were type A and 125 were type B.From 2013 to 2023,the detection rate of RSV in children showed an overall trend of initial increase followed by a decline,with higher detection rates in autumn and winter and lower rates in spring and summer.The RSV detection rate gradually decreased with age,with the highest rate observed in children<1 year old,accounting for 16.33%(80/490)of RSV-detection cases.Cough was the most common clinical symptom.Among the RSV-positive cases,36 involved co-infection with another virus,6 co-infected with three viruses,and 1 with mixed infection of four viruses.The most frequent co-infection was RSV and human coronavirus.[Conclusion]Children under 1 year of age are more susceptible to RSV infection,with cough being the predominant symptom.RSV infection in Pudong New Area,Shanghai,mainly occurs in winter.Targeted prevention and control measures should be taken for children under 1 year old during the winter season to reduce the risk of both RSV infection and co-infection with human coronavirus and influenza virus.关键词
急性呼吸道感染/呼吸道合胞病毒/混合感染/呼吸道病毒/儿童Key words
acute respiratory tract infection/respiratory syncytial virus/mixed infection/respiratory virus/children分类
医药卫生引用本文复制引用
于秋淼,叶楚楚,张黎,吴荣鑫,张雪纯,赵冰,王远萍..2013-2023年上海市浦东新区儿童呼吸道合胞病毒感染特征[J].上海预防医学,2025,37(5):410-415,6.基金项目
上海市加强公共卫生体系建设三年行动计划(2023-2025年)重点学科(GWVI-11.1-02) （2023-2025年）
