陕西师范大学学报（自然科学版）2025，Vol.53Issue(4)：32-53,22.DOI:10.15983/j.cnki.jsnu.2025302
融合光声技术的生物医学成像研究进展
Advancement in biomedical imaging integrating photoacoustic technology
摘要
Abstract
Photoacoustic imaging is an efficient,non-invasive biomedical imaging technique that combines the high contrast of optical imaging with the deep tissue penetration of ultrasound imaging.By reducing the effects of optical scattering,it provides clear internal imaging views.This paper discusses traditional photoacoustic imaging techniques,including photoacoustic tomography,photoacoustic microscopy,photoacoustic endoscopy,and photoacoustic molecular functional imaging.It also highlights four novel photoacoustic imaging technologies:photoacoustic elastography,photoacoustic-guided wavefront shaping,polarization photoacoustic imaging,and optical detection methods for photoacoustic signals.Compared to traditional methods,these new approaches incorporate advanced optical control and signal processing techniques to improve imaging accuracy and resolution.The main challenges faced by new photoacoustic imaging technologies include improving imaging speed,enhancing signal detectability,and optimizing system user-friendliness.This paper summarizes key scientific achievements in photoacoustic imaging for achieving high resolution and deep tissue imaging and provides an outlook for future development.In the future,photoacoustic imaging technology is expected to overcome current limitations through further hardware innovations and algorithm optimizations,particularly in real-time imaging,system simplicity.With the development of multimodal imaging systems,photoacoustic imaging may be combined with other imaging techniques,such as magnetic resonance imaging(MRI),computed tomography(CT),or positron emission tomography(PET),to provide more comprehensive biomedical imaging solutions.关键词
光声成像/生物医学光学/医学影像技术Key words
photoacoustic imaging/biomedical optics/medical imaging technology分类
数理科学引用本文复制引用
于音什,高杨,左超,马海钢..融合光声技术的生物医学成像研究进展[J].陕西师范大学学报（自然科学版）,2025,53(4):32-53,22.基金项目
国家自然科学基金(12204239,62275121) （12204239,62275121）
国家重大科研仪器研制项目(62227818) （62227818）
国家重点研发计划(2022YFB2804600,2022YFB2804603) （2022YFB2804600,2022YFB2804603）
江苏省自然科学基金(BK20220946) （BK20220946）
中央高校基本科研业务费专项资金(30923011024) （30923011024）
