天津工业大学学报2025，Vol.44Issue(3)：12-22,11.DOI:10.3969/j.issn.1671-024x.2025.03.002
碳纤维基皮质醇电化学汗液选择电极的制备与表征
Fabrication and characterization of cortisol-selective electrochemical sweat sensor based on carbon fiber substrate
摘要
Abstract
To develop a high-stability and high-sensitivity probe-free cortisol sensor for wearable sweat monitoring,a car-bon fiber(CF)-based composite electrode system was designed.A chitosan(CS)-Prussian blue(PB)/CF substrate was constructed through PB electrodeposition and CS coating via vacuum filtration.Subsequently,a molecularly imprinted polymer(MIP)layer was prepared using o—phenylenediamine as the functional monomer,ultimately forming a probe-free MIP/CS-PB/CF electrode.The morphology,electrochemical performance,and flexibility of the electrode were investigated.Results demonstrated that PB and CS synergistically enhanced electrode conduc-tivity,while the MIP layer enabled efficient recognition.The sensor achieved a detection limit of 0.235 nmol/L with a linear range from 1 to 105 nmol/L,exhibiting strong anti-interference against steroid analogs and common metabolites(selectivity coefficient＞2).The electrode maintained stable performance with＜1％resistance varia-tion after 1 200 bending cycles,demonstrated 3.01％relative standard deviation(RSD)in inter-batch re-peatability,and showed only 2.4％signal attenuation over 7 d.This electrode combines high sensitivity,selec-tivity,and mechanical stability,providing a reliable technical solution for wearable health monitoring systems.关键词
碳纤维/皮质醇/分子印迹聚合物/传感器/电化学/汗液Key words
carbon fiber/cortisol/molecularly imprinted polymer/sensor/electrochemical/sweat分类
信息技术与安全科学引用本文复制引用
刘皓,李至洁,罗丹,李君..碳纤维基皮质醇电化学汗液选择电极的制备与表征[J].天津工业大学学报,2025,44(3):12-22,11.基金项目
国家自然科学基金项目(52203276) （52203276）
天津市自然科学基金项目(18JCYBJC18500) （18JCYBJC18500）
国家重点研发计划"科技冬奥"重点专项(2019YFF0302105) （2019YFF0302105）
