现代医药卫生2025，Vol.41Issue(7)：1560-1563,1568,5.DOI:10.3969/j.issn.1009-5519.2025.07.005
早期肠内免疫营养治疗对远端胃癌改良三角吻合术后患者营养状态、免疫功能和炎症反应的影响
The effect of early enteral immunonutritional therapy on nutritional status,immune function and inflammatory response after modified triangular anastomosis for distal gastric cancer
摘要
Abstract
Objective To observe the effects of early enteral immunenutrition(EIN)on the nutritional status,immune function,and inflammatory response of patients after modified triangular anastomosis for dis-tal gastric cancer.Methods A total of 62 patients with distal gastric cancer who underwent modified triangu-lar anastomosis in our hospital were randomly divided into two groups.The control group 2 days after surger-y,PN was initiated through the central vein.The experimental group was prepared with personalized EIN and started taking it orally 2-3 days before surgery and 20-24 hours after surgery until discharge.Compare the nutritional,immune,and inflammatory indicators,complications,and length of hospital stay between two groups.Results After treatment,both groups showed significant improvement in various indicators,TFN,PA and other nutritional indexes in experimental groups were higher than those in control group(P<0.05).IgG,IgM,IgA,CD4+,CD8+,CD4+/CD8+were better than those in the control group(P<0.05).CRP and IL-6 were lower than those in the control group(P<0.05).The length of hospitalization and the complication rate was lower than that of control group(P<0.05).Conclusion The perioperative use of EIN in patients under-going modified triangular anastomosis for distal gastric cancer,compared with PN after surgery,which can im-prove nutritional status,enhance immune function,reduce inflammatory response,have fewer complications.关键词
围手术期/胃癌/EIN/营养状态/免疫功能/炎症反应Key words
Perioperative period/Gastric cancer/EIN/Nutritional status/Immune function/Inflammatory response/Length of hospital stay分类
医药卫生引用本文复制引用
简文红,劳景茂,韦小波..早期肠内免疫营养治疗对远端胃癌改良三角吻合术后患者营养状态、免疫功能和炎症反应的影响[J].现代医药卫生,2025,41(7):1560-1563,1568,5.基金项目
广西壮族自治区临床重点专科建设项目(普通外科)(桂卫医发[2022]17号) （普通外科）
钦州市科学研究与技术开发计划项目(20202730). （20202730）
