摘要
Abstract
Objective This study aims to systematically evaluate the risk of traffic accidents among pa-tients with OSAHS through a meta-analysis.It will compare research results from both domestic and interna-tional studies,assess the magnitude of this risk,and provide scientific evidence for the development and imple-mentation of effective traffic safety management strategies for OSAHS patients.Methods A systematic search was conducted in databases including CNKI,Wan Fang Data,VIP Data,PubMed,Embase,Cochrane Li-brary,and Web of Science to collect studies on the relationship between OSAHS and the risk of traffic acci-dents.The search period covered from the inception of these databases up to May 2024.We employed the Rev-Man 5.4 software as our tool.Results A total of 17 studies were incorporated into the analysis,comprising 121,560 patients with OSAHS and 1,300,609 individuals in the control group.The results revealed a signifi-cantly higher risk of traffic accidents among patients with OSAHS compared to those without OSAHS.In case-control studies,the risk of traffic accidents in the OSAHS group was greater than that in the non-OSAHS control group[OR=3.03,95%CI(2.36,3.90)].In cohort studies,the risk of traffic accidents among OSAHS patients increased by 77%[HR=1.77,95%CI(1.32,2.38)].Subgroup analysis showed that patients with severe OSAHS had a higher risk of traffic accidents[OR=6.06,95%CI(2.23,16.46)].The risk of traffic ac-cidents was similar among OSAHS patients in China[OR=3.44,95%CI(2.00,5.92)]and abroad[OR=2.40,95%CI(1.85,3.11)].CPAP treatment was found to reduce the risk of traffic accidents among OSAHS patients,but this reduction was not significantly different from the normal control group.Both Egger's test(t=2.01,P=0.073)and Begger's test(Z=1.78,P=0.075)indicated no significant publication bias.Conclusion OS-AHS significantly increases the risk of traffic accidents,especially for patients with severe OSAHS.Therefore,timely diagnosis and treatment for OSAHS patients may contribute to reducing the risk of traffic accidents.关键词
阻塞性睡眠呼吸暂停低通气综合征/交通事故/风险/驾驶员安全/Meta分析Key words
Obstructive sleep apnea hypopnea syndrome/Traffic accidents/Risk/Driver safety/Meta-analysis分类
医药卫生
