影像组学联合生物标志物预测肝癌微血管侵犯的研究进展
Research Progress of Radiomics Combined with Biomarkers for Predicting Microvascular Invasion in Liver Cancer
摘要
Abstract
Microvascular invasion is one of the critical factors influencing the prognosis of patients with hepatocellular carcinoma.Accurate preoperative prediction for its occurrence holds pivotal significance for the formulation of clinical individualized treatment decisions.Traditional diagnosis primarily relies on the evaluation of postoperative histopathological results,which exhibits a certain degree of lag.However,the emergence of radiomics features and biomarkers offers new insights for the preoperative prediction of mi-crovascular invasion.The preoperative prediction model based on radiomics and biomarkers is capable of precisely analyzing and efficiently predicting the occurrence risk of microvascular invasion from both macro-scopic imaging features and microscopic molecular levels,thereby providing multi-dimensional and precise scientific evidence for clinical decision-making.关键词
微血管侵犯/影像组学/生物标志物/肝癌/精准诊疗Key words
microvascular invasion/radiomics/biomarkers/hepatocellular carcinoma/precision diagnosis and treatment分类
医药卫生引用本文复制引用
梁静慧,王铭,陈婉婷,张宝璐荷,杜顺达,杨萌..影像组学联合生物标志物预测肝癌微血管侵犯的研究进展[J].协和医学杂志,2025,16(4):826-835,10.基金项目
国家自然科学基金联合基金项目(U22A2023) （U22A2023）
国家自然科学基金青年科学基金项目(A类)[原国家杰出青年科学基金项目](62325112) （A类）
国家重点研发计划项目(2023YFC2411705) （2023YFC2411705）
中央级公益性科研院所基本科研业务费项目(2024-RC320-02) （2024-RC320-02）
中央高水平医院临床科研专项(2022-PUMCH-D-002,2022-PUMCH-C-009) National Natural Science Foundation of China(U22A2023) （2022-PUMCH-D-002,2022-PUMCH-C-009）
National Natural Science Foundation of China(Grade A)[National Science Fund for Distinguished Young Scholars of China](62325112) （Grade A）
National Key Research and Devel-opment Program of China(2023YFC2411705) （2023YFC2411705）
Fundamental Research Funds for the Central Public-interest Scientific Institution of Chinese Academy of Medical Sciences(2024-RC320-02) （2024-RC320-02）
National High Level Hospital Clinical Research Funding(2022-PUMCH-D-002,2022-PUMCH-C-009) （2022-PUMCH-D-002,2022-PUMCH-C-009）
