畜牧兽医学报2025，Vol.56Issue(7)：3047-3056,10.DOI:10.11843/j.issn.0366-6964.2025.07.001
畜禽基因编辑抗病育种研究进展
Advances in Gene Editing for Disease Resistance Breeding in Livestock and Poultry
摘要
Abstract
In recent years,gene editing technology has been widely adopted due to its capability for precise and efficient modification of genetic information.By introducing disease-resistant genes or knocking out host genes essential for pathogen infection,this technology can effectively confer resistance to specific infectious diseases in animals,accelerating the development of new livestock and poultry breeds with enhanced disease resistance.Under the threat of major epidemics such as African swine fever(ASF),there is an urgent need not only to continuously strengthen conventional disease prevention and control measures but also to improve the innate disease resistance of livestock and poultry through genetic breeding.Therefore,cultivating breeds with high-efficiency disease resistance has become a pressing demand and core mission in current animal husbandry research and industrial practices.This paper reviews the current applications of gene editing technology in disease-resistant breeding of livestock and poultry,and prospectively outlines potential future directions and key research areas that warrant focused exploration.关键词
基因编辑/畜禽/抗病性/抗病育种Key words
gene editing/livestock and poultry/disease resistance/disease resistant breeding分类
农业科技引用本文复制引用
张帆,曾威,周傲..畜禽基因编辑抗病育种研究进展[J].畜牧兽医学报,2025,56(7):3047-3056,10.基金项目
国家农业生物育种重大项目(2023ZD0404305) （2023ZD0404305）
湖北省重点研发计划(2023BBB170) （2023BBB170）
湖北省自然科学基金创新群体(2024AFA027) （2024AFA027）
湖北省支持种业高质量发展资金项目(HBZY2023B006-04) （HBZY2023B006-04）
湖北省农业关键核心技术攻关项目(HBNYHXGG2023-7) （HBNYHXGG2023-7）
