畜牧兽医学报2025，Vol.56Issue(7)：3142-3151,10.DOI:10.11843/j.issn.0366-6964.2025.07.010
痒螨病皮肤损伤机制研究进展
Advances in Research on Skin Lesion of Psoroptic Mange
摘要
Abstract
Psoroptic mange,a prevalent ecto-parasitic disease affecting domestic and wild animals globally,is primarily characterized by skin lesions.Understanding the characteristics and mechanisms underlying these skin lesions is crucial for developing novel measures against psoroptic mange.This paper systematically reviews the pathological manifestations of skin lesions in psoroptic mange,focusing on the perturbations in the skin's physical and immune barriers during disease progression.Potential factors contributing to these alterationss are discussed,including the mechanical activity of Psoroptes mites and their excretory-secretory proteins(PsoES)which can impair the skin's physical barrier.Additionally,allergenic and other bioactive molecules within the PsoES can infiltrate the weakened physical barrier,disrupting the immune barrier and thereby accelerating the onset and and progression of skin damage.The objective of this review is to provide insights and directional guidance for the development of novel anti-mite therapeutics,ultimately aiming to provide new perfectives on the prevention and control of psoropic mange.关键词
痒螨病/皮肤损伤/皮肤损伤形成因素Key words
psoroptic mange/skin lesion/causative factors of skin lesion分类
农业科技引用本文复制引用
樊洁,古小彬..痒螨病皮肤损伤机制研究进展[J].畜牧兽医学报,2025,56(7):3142-3151,10.基金项目
四川农业大学学科双支计划(2221993268) （2221993268）
