心脑血管病防治2025，Vol.25Issue(6)：36-40,5.DOI:10.3969/j.issn.1009-816x.2025.06.008
急性心肌梗死患者Adropin水平及其与侧支循环状态的相关性
Adropin level in patients with acute myocardial infarction and its correlation with collateral circulation status
摘要
Abstract
Objective To investigate the relationship between coronary collateral circulation status and Adropin level in patients with acute myocardial infarction.Methods A total of 274 patients with acute myocardial infarction who underwent percutaneous coronary intervention(PCI)at the First Affiliated Hospital of Hebei North University from March,2023 to April,2024 were selected as the research object.All patients underwent coronary angiography.According to their coronary collateral circulation status,the patients were divided into a good circulation group(46 cases)and a poor circulation group(228 cases).General data,clinical parameters,and admission Adropin levels of patients from the two groups were compared.Pearson correlation analysis was used to evaluate the association between the coronary collateral circulation status and Adropin levels.Multivariate Logistic regression was applied to analyze the influencing factors of poor coronary collateral circulation.Results The proportion of acute myocardial infarction patients with good coronary collateral circulation prior to PCI was 16.79%.There were statistically significant differences between the good and poor circulation groups in angina pectoris duration,white blood cell count,adrenaline and Adropin level,infarct location,and symptom-to-treatment time(x2/t/U=8.668,3.968,7.392,7.791,6.500,2.666;all P<0.05).Pearson correlation analysis showed that Rentrop classification was positively correlated with Adropin level(r=0.683,P<0.05).Multivariate Logistic regression analysis revealed that angina pectoris duration(OR=0.314),symptom-to-treatment time(OR=0.567),white blood cell count(OR=1.278),adrenaline(OR=0.948)and Adropin level(OR=0.902)were influencing factors for coronary collateral circulation status(P<0.05).Conclusion Acute myocardial infarction patients with good coronary collateral circulation status have higher admission Adropin levels.Adropin level is identified as an influencing factor for the coronary collateral circulation status.关键词
急性心肌梗死/Adropin/冠状动脉侧支循环/经皮冠状动脉介入治疗Key words
Acute myocardial infarction/Adropin/Coronary collateral circulation/Percutaneous coronary intervention引用本文复制引用
郝翠君,王蕊,马逸平,张雪萍,刘亚男,秦少强..急性心肌梗死患者Adropin水平及其与侧支循环状态的相关性[J].心脑血管病防治,2025,25(6):36-40,5.基金项目
河北省2020年度医学科学研究课题计划(20200509) （20200509）
