右江医学2025，Vol.53Issue(6)：522-527,6.DOI:10.3969/j.issn.1003-1383.2025.06.007
GCS评分、Rotterdam-CT评分联合血清SOD水平对不同程度颅脑损伤患者预后的应用价值
Application value of GCS score,Rotterdam-CT score and serum SOD level in the prognosis of patients with different degrees of brain injury
摘要
Abstract
Objective To explore the application value of the Glasgow coma scale(GCS),Rotterdam-CT score combined with superoxide dismutase(SOD)levels in evaluating the degree of injury and prognosis in patients with traumatic brain injury(TBI).Methods 98 patients with TBI admitted to the Department of Neurosurgery at the First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine from March 2022 to September 2023 were selected.All patients were classified into mild group,moderate group,and severe group according to their GCS scores.Differences in SOD levels and Rotterdam-CT scores among patients with varying degrees of injury severity were compared,and correlation between these two indicators and the severity of TBI was analyzed.Univariate and multivariate regression analyses were conducted to identify independent influencing factors for poor prognosis in TBI patients.Receiver operating characteristic(ROC)curve was used to analyse the evaluation value of GCS scores,Rotterdam-CT scores,and SOD levels for poor progno-sis in TBI patients.Results ① There were statistically significant differences in SOD levels and Rotterdam-CT scores among the three groups of patients(P<0.001).② Pearson correlation analysis showed that SOD levels were negatively correlated with the severity of TBI,while the Rotterdam-CT score was positively correlated with the severity of TBI(P<0.001).③ The results of the ROC curve analysis showed that the area under the curve(AUC)for predicting the prognosis of TBI patients by the GCS score,Rotterdam-CT score,and SOD level alone and in combination were 0.879,0.873,0.901,and 0.959,respectively.Conclusion GCS score,Rotterdam CT score,and SOD level are closely related to poor prognosis of TBI patients,and the combination of the three is more accurate in evaluating the prognosis of TBI patients.关键词
颅脑损伤/格拉斯哥昏迷评分/Rotterdam-CT评分/超氧化物歧化酶/损伤程度/预后Key words
traumatic brain injury/Glasgow coma score(GCS)/Rotterdam-CT score/superoxide dismutase(SOD)/damage degree/prognosis分类
医药卫生引用本文复制引用
陈锐,林永雙,李子明,朱云中,周庆,周海静,卢双宏,黄毅..GCS评分、Rotterdam-CT评分联合血清SOD水平对不同程度颅脑损伤患者预后的应用价值[J].右江医学,2025,53(6):522-527,6.基金项目
广西医疗卫生适宜技术开发与推广应用项目(S2023117) （S2023117）
广西壮族自治区卫生健康委员会自筹课题(Z-A20240789) （Z-A20240789）
