眼科新进展2025，Vol.45Issue(8)：635-643,9.DOI:10.13389/j.cnki.rao.2025.0109
1990-2021年全球、区域和国家眼癌疾病负担及变化趋势
Global,regional and national burdens of eye cancer and change trends from 1990 to 2021
摘要
Abstract
Objective To assess the global,regional,and national burdens of eye cancer between 1990 and 2021,examine its change trends with the age,sex,geographic location,and socio-demographic index(SDI)level,and provide scientific evidence for the development of eye cancer prevention and control strategies.Methods Based on the data from the Global Burden of Disease(GBD)study,the global burden of eye cancer was evaluated using the indicator system inclu-ding incidence,prevalence,mortality,and disability-adjusted life years(DALYs).The change trend of the burden of eye cancer with time was quantified with Join-point regression.Frontier analysis methods were used to evaluate the relationship between the burdens of eye cancer with SDI.Results From 1990 to 2021,the global incidence,age-standardized inci-dence rate(ASIR),prevalence and age-standardized prevalence rate(ASPR)of eye cancer showed an upward trend over time.Conversely,the mortality,age-standardized mortality rate(ASMR),DALYs,and age-standardized DALY rate(ASDR)declined during the same period.All the above indicators in males were higher than those in females.Regionally,Eastern Sub-Saharan Africa bore the highest disease burden,while Oceania had the lowest.It should be noted that East Asia experienced the most significant increase in ASIR,and Southern Sub-Saharan Africa showed the greatest rise in ASPR.Meanwhile,Southern Latin America demonstrated the most pronounced decrease in both ASIR and ASPR.East Asia also re-corded the largest reductions in ASMR and ASDR.At the national level,Malawi had the highest disease burden in 2021.To-kelau exhibited the most substantial increase while Norway showed the greatest decrease in disease burden.Age-specific analysis revealed a bimodal distribution,with children under 5 years and adults over 80 being the most affected groups.Furthermore,SDI-based analysis indicated a wave-like relationship between SDI and ASIR/ASPR,and both ASMR and AS-DR declined with the increasing SDI.Conclusion The global burden of eye cancer shows a decline trend generally.The difference in the burden of eye cancer between regional and national levels may be related to medical resource allocation and public health policies.The results of this study provide scientific evidence for the development of tailored eye cancer prevention and control strategies.It is recommended that more attention should be paid to high-burden regions,resource distribution should be optimized,early screening should be enhanced,and targeted interventions for different age and gen-der groups should be implemented.关键词
眼癌/全球疾病负担/死亡率/患病率/发病率/伤残调整生命年Key words
eye cancer/global burden of disease/mortality/prevalence/incidence/disability-adjusted life years分类
医药卫生引用本文复制引用
谷珍珍,陈凯铭,陈曦,郝晓凤,谢立科..1990-2021年全球、区域和国家眼癌疾病负担及变化趋势[J].眼科新进展,2025,45(8):635-643,9.基金项目
中国中医科学院眼科医院高水平中医医院揭榜挂帅项目(编号:GSP4-02-2,GSP4-02-3) （编号:GSP4-02-2,GSP4-02-3）
中国中医科学院眼科医院高水平中医医院"医疗机构制剂及中药新药研发"项目(编号:GSP3-05) （编号:GSP3-05）
中国中医科学院眼科医院院级科研启动基金项目(编号:Kxy-202202) （编号:Kxy-202202）
卫健委老龄司老年眼健康项目(编号:2023-234) （编号:2023-234）
