临床医学工程2025，Vol.32Issue(7)：719-723,5.DOI:10.3969/j.issn.1674-4659.2025.07.0719
全自动生化分析仪联合尿液分析仪在2型糖尿病诊断及病情评估中的应用
Application of Fully Automatic Biochemical Analyzer Combined with Urine Analyzer in the Diagnosis and Disease Evaluation of Type 2 Diabetes Mellitus
摘要
Abstract
Objective To analyze the application value of fully automatic biochemical analyzer combined with urine analyzer in the diagnosis and disease evaluation of type 2 diabetes mellitus.Methods 140 patients with suspected type 2 diabetes mellitus who underwent physical examination in our hospital from December 2023 to June 2024 were retrospectively selected as the research objects,and the levels of blood sugar and urine sugar were tested by CA-800 C fully automatic biochemical analyzer and US-2000PH automatic urine analyzer.The results of oral glucose tolerance test were used as the gold standard to analyze the diagnostic efficacy(sensitivity,specificity,accuracy)of single and combined detection of fully automatic biochemical analyzer and urine analyzer for type 2 diabetes mellitus.According to the disease condition of patients with type 2 diabetes mellitus(whether complicated with nephropathy),they were divided into the diabetic nephropathy group and the non-diabetic nephropathy group,and the blood glucose indicators[fasting blood glucose(FPG),2 h postprandial blood glucose(2hPG),glycosylated hemoglobin(HbA1c)]detected by fully automatic biochemical analyzer and uric acid(UA),urea nitrogen(BUN)detected by automatic urine analyzer were compared between the two groups.The receiver operating characteristic(ROC)curve was drawn to analyze the evaluation value of single and combined detection of fully automatic biochemical analyzer and urine analyzer for patients with type 2 diabetes mellitus.Results Among 140 patients with suspected type 2 diabetes mellitus,84 cases were positive and 56 cases were negative according to the gold standard test.83 positive cases(including 81 true positive cases)and 57 negative cases(including 54 true negative cases)were detected by fully automatic biochemical analyzer combined with urine analyzer.The sensitivity,specificity and accuracy of combined detection in the diagnosis of type 2 diabetes mellitus were higher than those of single detection(P＜0.05).The levels of FPG,2hPG,HbA1c,UA,BUN in the diabetic nephropathy group were higher than those in the non-diabetic nephropathy group(P＜0.05).ROC curve showed that the area under the curve(AUC)of the combined detection of fully automatic biochemical analyzer and urine analyzer to evaluate the disease condition of type 2 diabetes mellitus was 0.930,higher than that of single detection.Conclusions The application value of fully automatic biochemical analyzer combined with urine analyzer in the diagnosis and disease evaluation of type 2 diabetes mellitus is high,the levels of FPG,2hPG,HbA1c,and UA and BUN detected by fully automatic biochemical analyzer combined with urine analyzer respectively can be used as common indicators for clinical evaluation of type 2 diabetes mellitus complicated with nephropathy,but it still needs to be considered comprehensively in combination with the actual situation of patients.关键词
全自动生化分析仪/尿液分析仪/2型糖尿病/病情评估Key words
Fully automatic biochemical analyzer/Urine analyzer/Type 2 diabetes mellitus/Disease evaluation分类
医药卫生引用本文复制引用
高晓嫱..全自动生化分析仪联合尿液分析仪在2型糖尿病诊断及病情评估中的应用[J].临床医学工程,2025,32(7):719-723,5.基金项目
定西市科技计划项目(DX2024AY05) （DX2024AY05）
