中草药2025，Vol.56Issue(14)：5311-5323,13.DOI:10.7501/j.issn.0253-2670.2025.14.033
中药挥发油分离纯化技术的研究进展
Research progress on separation and purification technologies of essential oils in traditional Chinese medicine
摘要
Abstract
Volatile oils of traditional Chinese medicine(TCM),also known as TCM essential oils,represent a crucial category of bioactive components in Chinese herbal medicines.They exhibit diverse biological activities such as antioxidant,antibacterial,anti-inflammatory,and antitumor effects.Their chemical composition primarily consists of monoterpenes,sesquiterpenes,and their derivatives.The separation and purification of active components in essential oils,along with the removal of harmful substances like toxic and photosensitive compounds,are of great significance for elucidating the pharmacodynamic material basis of volatile oils,screening bioactive components,quality control,and further development and utilization.Currently,the separation and purification of essential oils mainly rely on liquid-liquid extraction technology,molecular distillation technology,fractional distillation technology,chromatography technology,and crystallization technology.Based on literature from the past decade in databases such as PubMed and CNKI,this article systematically summarizes and analyzes the working principles,application advances,and existing limitations of essential oil separation and purification technologies.The aim is to provide scientific references for the efficient separation and purification as well as safe application of TCM essential oils,thereby promoting the further development of the TCM essential oil industry.关键词
中药挥发油/分离纯化/液-液萃取技术/分子蒸馏技术/精馏技术/色谱技术/结晶技术Key words
traditional Chinese medicine essential oils/separation and purification/liquid-liquid extraction technology/molecular distillation technology/distillation technology/chromatography technology/crystallization technology分类
医药卫生引用本文复制引用
郭园园,李慧婷,杨明,叶玉祯,张学浩,黄小英..中药挥发油分离纯化技术的研究进展[J].中草药,2025,56(14):5311-5323,13.基金项目
江西省赣江新区重点研发计划项目(20230007) （20230007）
国家自然科学基金资助项目(82404878) （82404878）
江西省自然科学基金资助项目(20242BAB20456) （20242BAB20456）
江西省"赣鄱英才"创新领军人才项目(S2024LQCQ0477) （S2024LQCQ0477）
