中风与神经疾病杂志2025，Vol.42Issue(7)：594-599,6.DOI:10.19845/j.cnki.zfysjjbzz.2025.0113
前哨性头痛在卒中患者急性期的发展演变及预后关系的研究
Progression of sentinel headache in patients in the acute stage of stroke and its association with prognosis
摘要
Abstract
Objective Sentinel headache(SH)refers to new-onset headache or existing headache with altered char-acteristics that occurs within seven days before stroke in patients,and this study aims to investigate the incidence rate and clinical features of SH in stroke patients and its association with prognosis.Methods A total of 145 stroke patients who were admitted to Department of Neurology,The First Affiliated Hospital of Xi'an Jiaotong University,from August 2022 to April 2023 were enrolled based on inclusion/exclusion criteria,and general information was collected.According to the presence or absence of SH,they were divided into headache and control group.The features of SH were summarized,and follow-up was performed after 1 year to analyze the association between SH and prognosis.Results Among the 145 pa-tients with stroke,30(20.7%)developed SH,with the subtypes of intracerebral hemorrhage(9 patients,25.7%),cere-bral infarction(15 patients,18.9%),transient ischemic attack(3 patients,14.3%),and subarachnoid hemorrhage(3 pa-tients,30.0%).Conclusion SH may occur in all stroke patients,with a prevalence rate of 20.7%.The manifestations of SH include migraine-like headache,tension-type headache,and cluster-like headache.The results of this study do not establish an association between SH and 1-year prognosis in stroke patients,and further studies are needed in the future.关键词
脑卒中/前哨性头痛/脑血管病/临床特征/预后Key words
Stroke/Sentinel headache/Cerebral vascular disease/Clinical characteristics/Prognosis分类
医药卫生引用本文复制引用
柳书涵,袁博博,徐越,罗国刚,卫萌..前哨性头痛在卒中患者急性期的发展演变及预后关系的研究[J].中风与神经疾病杂志,2025,42(7):594-599,6.基金项目
国家重点研发项目(2023YFC2508705) （2023YFC2508705）
陕西省重点研发计划项目(2020SF-335) （2020SF-335）
