摘要
Abstract
As the third-level diagnosis of migraine,recurrent gastrointestinal disturbance is a group of disorders with recurrent episodic attacks of abdominal pain and/or discomfort and nausea and/or vomiting that may be associated with mi-graine,and it is a clinical syndrome with the core symptom of abdominal pain,with the presence of clinical and neurobio-logical associations.This article reviews the similarities of the two diseases from the aspects of epidemiological characteris-tics,gender distribution tendency,clinical course,auxiliary examination,and treatment response,as well as three poten-tial mechanisms in pathophysiology.This strong association between functional recurrent abdominal pain and migraine sug-gests that although there is no definitive evidence,adult functional recurrent abdominal pain,or at least its specific sub-sets,may belong to the spectrum of migraine.In other words,functional recurrent abdominal pain itself without headache may be a"migraine phenomenon".In the future,it is necessary to conduct more rigorously designed observational studies on the association between the two diseases to clarify such possibility,in order to provide strong supporting evidence for the diagnosis and treatment of patients with functional recurrent abdominal pain and migraine and relieve pain as soon as possible.关键词
功能性复发性腹痛/偏头痛/中枢敏化/肠-脑轴Key words
Functional recurrent abdominal pain/Migraine/Central sensitization/Gut-brain axis分类
医药卫生
