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我国百白破疫苗免疫程序调整对临床百日咳的潜在影响

胡亚红 姚开虎

中国当代儿科杂志2025,Vol.27Issue(7):786-791,6.
中国当代儿科杂志2025,Vol.27Issue(7):786-791,6.DOI:10.7499/j.issn.1008-8830.2501077

我国百白破疫苗免疫程序调整对临床百日咳的潜在影响

Potential impact of adjusting immunization procedure for diphtheria-tetanus-pertussis vaccine on pertussis in clinical practice

胡亚红 1姚开虎1

作者信息

  • 1. 国家儿童医学中心/首都医科大学附属北京儿童医院/北京市儿科研究所感染与微生物研究室/国家呼吸系统疾病临床医学研究中心/国家儿童感染与过敏性疾病临床监测中心/儿科学国家重点学科/儿科重大疾病研究教育部重点实验室/北京重大呼吸道传染病研究中心,北京 100045
  • 折叠

摘要

Abstract

In recent years,the incidence rate of pertussis in China has been steadily increasing,presenting an increasingly severe challenge for disease prevention and control.To strengthen the immune barrier in the population and effectively curb the spread of pertussis,National Disease Control and Prevention Administration of China and other relevant authorities optimized the immunization procedure for diphtheria-tetanus-pertussis vaccine,with the new procedure implemented in 2025.This adjustment includes three key measures:advancing the initial dose of the vaccine from 3 months to 2 months of age,extending the interval between primary immunization doses from 1 month to 2 months,and adding an extra dose of acellular diphtheria-tetanus-pertussis vaccine at 6 years of age.This article discusses potential changes in the epidemiology and clinical manifestations of pertussis following such adjustments for immunization procedure,and awareness of these changes will facilitate the accurate identification of pertussis cases,which is crucial for evaluating the impact of these adjustments and further optimizing immunization strategies.

关键词

百日咳/百白破疫苗/免疫程序/流行病学

Key words

Pertussis/Diphtheria-tetanus-pertussis vaccine/Immunization procedure/Epidemiology

引用本文复制引用

胡亚红,姚开虎..我国百白破疫苗免疫程序调整对临床百日咳的潜在影响[J].中国当代儿科杂志,2025,27(7):786-791,6.

中国当代儿科杂志

OA北大核心

1008-8830

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