中国动脉硬化杂志2025，Vol.33Issue(6)：515-522,8.DOI:10.20039/j.cnki.1007-3949.2025.06.008
EuroSCOREⅡ评分及Gensini评分与冠心病PCI术后主要不良心血管事件发生的相关性研究
Study on the correlation between EuroSCOREⅡscore,Gensini score and the occur-rence of major adverse cardiovascular events in patients with coronary heart disease after PCI
摘要
Abstract
Aim To investigate the correlation between the new version of the European System for Cardiac Op-erative Risk Evaluation Ⅱ(EuroSCORE Ⅱ)score,Gensini score and the occurrence of major adverse cardiovascular e-vents(MACE)after percutaneous coronary intervention(PCI)in patients with coronary heart disease(CHD).Meth-ods A total of 203 CHD patients undergoing PCI treatment admitted to the Department of Cardiovascular Surgery of the First Affiliated Hospital of Air Force Military Medical University from January 2021 to March 2023 were selected as the study objects.Depending on whether MACE happened or not,they were divided into MACE group and non-MACE group.The clinical data of the two groups of patients was compared.Pearson's correlation coefficient was used to analyze the cor-relation between EuroSCOREⅡscore and Gensini score;Logistic regression model was used to evaluate the risk factors for the development of MACE after PCI in patients with CHD;and ROC curves was used to analyze the predictive value of pre-dictive indexes for the development of MACE after PCI in patients with CHD.Results In 203 cases of CHD patients who underwent PCI,65 of them experienced MACE during the 1-year postoperative follow-up(32.02%).The age,rate of history of diabetes mellitus,rate of Killip classification≥gradeⅡ,rate of≥2 diseased vessels,rate of≥2 stents,EuroSCOREⅡscore,and Gensini score of the MACE group were higher than those of the non-MACE group,and the differ-ences were all statistically significant(P<0.05).The results of the Pearson's correlation analysis indicated that there was a positive correlation between the EuroSCOREⅡscore and Gensini score(r=0.200,P=0.004).Logistic regression model analysis showed that age increase,Killip classification≥gradeⅡ,high EuroSCOREⅡscore,and high Gensini score were independent risk factors for the development of MACE after PCI in CHD patients(P<0.05).ROC curve anal-ysis showed that age increase,Killip classification≥gradeⅡ,EuroSCOREⅡscore,Gensini score,and combined predic-tion had statistical significance in determining the occurrence of MACE after PCI(P<0.05);The area under the curve(AUC)of combinedpredictionwas0.953,95%CI was 0.928～0.979,sensitivity was 0.892,specificity was 0.891,in-dicating high predictive value.Conclusion Age increase,Killip classification≥gradeⅡ,high EuroSCOREⅡscore,and high Gensini score are independent risk factors for the occurrence of MACE after PCI in patients with CHD,and all of them have a certain predictive value for MACE after PCI in patients with CHD,and the combined predictive value is higher.关键词
冠心病/经皮冠状动脉介入治疗/主要不良心血管事件/新版欧洲心脏手术风险评分系统/Gensini评分/重症监护Key words
coronary heart disease/percutaneous coronary intervention/major adverse cardiovascular events/new version of the European System for Cardiac Operative Risk Evaluation Ⅱ/Gensini score/intensive care分类
医药卫生引用本文复制引用
刘雪凤,李兰香,樊苗,张毅..EuroSCOREⅡ评分及Gensini评分与冠心病PCI术后主要不良心血管事件发生的相关性研究[J].中国动脉硬化杂志,2025,33(6):515-522,8.基金项目
陕西省自然科学基金项目(2024JC-YBMS-635) （2024JC-YBMS-635）
