摘要
Abstract
Objective To investigate the bacterial distribution and drug sensitivity results of pus in pa-tients with anal fistula,and to provide references for clinicians to reasonably select antibacterial drugs.Methods The medical records of 1188 inpatients with anal fistula treated in our hospital from January 2023 to December 2024 were retrospectively analyzed,and the results of bacterial culture and drug sensitiv-ity test were analyzed.Results A total of 316 pathogenic bacteria were detected,including 293 Gram-negative bacteria,accounting for 92.72％.The top three were 205 strains of Escherichia coli,53 strains of Klebsiella pneumoniae and 18 strains of Proteus mirabilis.There were 23 Gram-positive bacteria,account-ing for 7.28％,mainly 19 strains of Staphylococcus aureus.Analyzing the results of drug sensitivity tests of common antibacterial drugs,the top five with high sensitivity rates were meropenem,piperacillin/tazobactam,cefoperazone/sulbactam,amikacin and cefoxitin,with sensitivity rates ranging from 90.22％to 100.00％.The top five with high resistance rates were ampicillin,cotrimoxazole,cefazolin,levofloxacin and cefuroxime,with resistance rates ranging from 30.07％to 77.90％.Staphylococcus aureus had rela-tively high sensitivity rates to oxacillin,rifampicin,chloramphenicol and cefoxitin,and relatively high re-sistance rates to penicillin,azithromycin and erythromycin.Conclusion Anal fistula infections are mainly caused by Gram-negative bacteria,with Escherichia coli being the most common,and Gram-positive bacte-ria are mainly Staphylococcus aureus.Clinicians should fully consider factors such as pathogenic bacteria,drug sensitivity rates,and resistance rates when rationally selecting antibacterial drugs.关键词
肛瘘/细菌培养/敏感率/耐药率Key words
Anal fistula/Bacterial culture/Sensitivity rate/Resistance rate
