中国免疫学杂志2025，Vol.41Issue(7)：1616-1623,8.DOI:10.3969/j.issn.1000-484X.2025.07.012
ncRNAs调控TAMs代谢重编程在肿瘤治疗中的研究进展
Roles of ncRNAs regulating metabolic reprogramming of TAMs in oncotherapy
摘要
Abstract
Vast majority of human RNA are non-coding RNA(ncRNA),which can regulate physiological activities and affects functions on cells.Although each part of them is obscure,they are involved in different levels of gene regulation,from epigene-tic gene silencing to post transcriptional regulation.Metabolic reprogramming of tumor-associated macrophages(TAMs)can promote tumor progression and is closely related to activation phenotypes of anti-tumor(M1)or pro-tumor(M2).A lot of ncRNAs are involved in metabolic reprogramming of TAMs,reshaping tumor microenvironment and playing a key role in tumor progression.Improving understanding of effect on ncRNA regulating metabolic reprogramming of TAMs may provide new methods for developing effective clinical treatments.关键词
非编码RNA/肿瘤相关巨噬细胞/代谢重编程Key words
Non-coding RNA/Tumor-associated macrophages/Metabolic reprogramming分类
医药卫生引用本文复制引用
王赞涵,孙志宏,秦鸿雁,胡昳旸..ncRNAs调控TAMs代谢重编程在肿瘤治疗中的研究进展[J].中国免疫学杂志,2025,41(7):1616-1623,8.基金项目
国家自然科学基金重点项目(82230015) （82230015）
陕西省科技创新团队项目(2021TD-36) （2021TD-36）
陕西省自然科学基金项目(2020JM-334). （2020JM-334）
