中国脑血管病杂志2025，Vol.22Issue(6)：424-429,6.DOI:10.3969/j.issn.1672-5921.2025.06.007
替罗非班在急性缺血性卒中机械取栓治疗中的研究进展
Research progress of tirofiban in the treatment of mechanical thrombectomy in patients with acute ischemic stroke
魏衍鹏 1汤子豪 2徐佳明 2孙军2
作者信息
- 1. 325000 温州医科大学定理临床学院
- 2. 温州市中心医院泛血管疾病管理中心实验室
- 折叠
摘要
Abstract
Mechanical thrombectomy,which improves the successful vascular recanalization rate and neurological functional prognosis in patients with acute ischemic stroke(AIS)caused by anterior circulation large vessel occlusion,has become one of the primary therapeutic strategies.Among the pharmacologic adjuvant therapies for mechanical thrombectomy,tirofiban(a platelet glycoprotein Ⅱ b/Ⅲ a receptor antagonist)has attracted significant attention due to its antithrombotic mechanism.This article summarized the research progress of tirofiban in the mechanical thrombectomy treatment of AIS patients from the perspectives of pharmacological mechanisms,administration timing,selection of eligible populations,and dosage regimens.It also analyzed the clinical application value and existing controversies of tirofiban,aiming to provide a scientific basis for optimizing the AIS treatment system.关键词
急性脑梗死/替罗非班/机械取栓术/综述Key words
Acute ischemic stroke/Tirofiban/Mechanical thrombectomy/Review引用本文复制引用
魏衍鹏,汤子豪,徐佳明,孙军..替罗非班在急性缺血性卒中机械取栓治疗中的研究进展[J].中国脑血管病杂志,2025,22(6):424-429,6.
