中国全科医学2025，Vol.28Issue(25)：3104-3109,6.DOI:10.12114/j.issn.1007-9572.2023.0820
可穿戴式心音心电远程监测设备用于心力衰竭的研究
Wearable Acoustic-electrocardiographic Remote Monitoring Device for Heart Failure
摘要
Abstract
Background Early assessment and prompt treatment for heart failure patients can prevent the occurrence of cardiac adverse events.Effective diagnostic tools are particularly crucial for these patients.Acoustic Cardiography(ACG),as an efficient and non-invasive bedside screening tool,can be used to evaluate the severity of heart failure.Objective To investigate the feasibility of using a wearable acoustic-electrocardiographic remote monitoring device for dynamic cardiac function assessment during heart failure treatment.Methods This prospective single-arm self-controlled study randomly enrolled 60 patients with acute heart failure admitted to the Department of Cardiology,the first Affiliated Hospital of Kunming Medical University,from October 2020 to December 2020.Key parameters,including electro-mechanical activation time(EMAT),EMAT percentage(EMAT%),N-terminal pro-B-type natriuretic peptide(NT-proBNP),and body weight,were measured on admission days 1,2,3,5,and discharge day.Echocardiographic parameters were assessed on admission and discharge days.Trends in parameter changes and consistency among indicators were analyzed.Results Among the 60 patients(35 males,25 females),the average hospitalization duration was(7.9±3.2)days.One-way repeated measures ANOVA revealed statistically significant differences in EMAT,EMAT%,NT-proBNP,and body weight across time points(FEMAT=6.978,P<0.01;FEMAT%=3.108,P<0.05;FNT-proBNP=8.678,P<0.01;Fweight=27.246,P<0.01).Pairwise comparisons demonstrated sequential decreases in these parameters from admission to discharge(P<0.01).No significant differences were observed in echocardiographic parameters before and after treatment(P>0.05).Time-adjusted repeated measures ANOVA confirmed consistent trends between EMAT and NT-proBNP changes during hospitalization(Day 1:β=67.724,P<0.01;Day 2:β=56.876,P<0.01;Day 3:β=38.503,P<0.01;Day 5:β=23.969,P<0.01;discharge:β=16.851,P<0.05).Conclusion Compared to bedside echocardiography(e.g.,LVEF)and NT-proBNP testing,the wearable acoustic-electrocardiographic remote monitoring device offers non-invasive,convenient,and cost-effective advantages.The device captures dynamic changes in acoustic and electrocardiographic parameters that correlate with clinical improvements in heart failure patients,suggesting its potential for remote cardiac function monitoring and timely detection of disease progression.关键词
心力衰竭/心音心电图/机电激活时间/可穿戴设备Key words
Heart failure/Heart sound electrocardiogram/Electromechanical activation time/Wearable devices分类
医药卫生引用本文复制引用
刘文洁,孙煌,罗薇,陈旋,彭云珠,李锐洁,马米尔..可穿戴式心音心电远程监测设备用于心力衰竭的研究[J].中国全科医学,2025,28(25):3104-3109,6.基金项目
云南省"兴滇人才"青年人才项目(rlqb2020008) （rlqb2020008）
云南省基础研究计划(昆医联合专项)(202301AY070001-136) （昆医联合专项）
云南省高层次卫生技术人员(后备人才)(H-2018031) （后备人才）
云南省科技厅基础研究计划(202101AY070001-131) （202101AY070001-131）
