中国兽医杂志2025，Vol.61Issue(7)：83-88,6.DOI:10.20157/j.cnki.zgsyzz.2025.07.010
沙门菌诱导宿主细胞炎症小体应答研究进展
Research Progress on Inflammasome Responses in Host Cells induced by Salmonella
摘要
Abstract
The inflammasome response in host cells is a key research focus in understanding the interaction between Salmonella and host.Infection with Salmonella activates the host cell inflammasome signaling pathway,which,on one hand,induces pyroptosis and facilitates early bacterial clearance,and on the other hand,mediates inflammasome-dependent hyperactivation of immune cells,thereby promoting the initiation of specific adaptive immune responses.This review summarizes recent advances in the understanding of inflammasome responses induced by Salmonella infection and their impact on the development of adaptive immunity,aiming to provide references for elucidating the pathogenesis of Salmonella and advancing strategies for disease prevention and control.关键词
沙门菌/炎症小体/细胞焦亡/细胞超活化/获得性免疫Key words
Salmonella/inflammasome/pyroptosis/cell hyperactivation/adaptive immunity分类
农业科技引用本文复制引用
陈亚琴,潘志明,焦新安,胡茂志..沙门菌诱导宿主细胞炎症小体应答研究进展[J].中国兽医杂志,2025,61(7):83-88,6.基金项目
国家重点研发计划(2022YFC2604204) （2022YFC2604204）
国家自然科学基金(32473041) （32473041）
