中国医科大学学报2025，Vol.54Issue(7)：648-652,669,6.DOI:10.12007/j.issn.0258-4646.2025.07.013
细胞消融在神经生物学和神经系统疾病研究中的应用
Application of cell ablation in neurobiological and neurological system disease research
摘要
Abstract
Cell ablation has recently emerged as a valuable technique for investigating cell lineage and function during the development of organisms.The nervous system contains diverse cellular populations,whose roles under physiological and pathological conditions are still not fully understood.Various cell ablation methods have been reported to specifically ablate different types of cell populations in the nervous system and have also been used to study cellular functions under physiological conditions as well as the pathogenesis of neurologi-cal system diseases.In this article,we have summarized common cell ablation techniques and focus on their applications in neurobio-logical and neurological system disease research.关键词
细胞消融/神经系统/白喉毒素/胱天蛋白酶Key words
cell ablation/nervous system/diphtheria toxin/caspase分类
医药卫生引用本文复制引用
陈翀,王思元,赫小乔,赵伟东..细胞消融在神经生物学和神经系统疾病研究中的应用[J].中国医科大学学报,2025,54(7):648-652,669,6.基金项目
国家自然科学基金(32271203,U23A20427) （32271203,U23A20427）
中国医科大学大学生创新创业训练计划(202410159005) （202410159005）
