中国医学科学院学报2025，Vol.47Issue(3)：390-395,6.DOI:10.3881/j.issn.1000-503X.16693
继发性甲状腺鳞状细胞癌的超声特征
Ultrasound Characteristics of Secondary Squamous Cell Carcinoma of the Thyroid
摘要
Abstract
Objective To analyze the ultrasonographic features of secondary squamous cell carcinoma of the thyroid(SSCC-T)and evaluate the diagnostic value of ultrasound.Methods A retrospective analysis was conducted on clinical and ultrasonographic data from 12 patients with pathologically confirmed SSCC-T treated at Beijing Friendship Hospital,Capital Medical University between January 2016 and January 2025.Evaluated parameters included lesion size,echogenicity,edge,vascularity,calcification,and cervical lymph node metastasis.Descriptive statistical analysis was performed to analyze the ultrasonographic features of SSCC-T,and Fisher's exact test was conducted to analyze the correlation between different ultrasound classifications and thyroid dysfunction.Results The 12 patients showed the following ultrasound classifications:nodular type(50.0％,6/12),diffuse type(33.3％,4/12),and mixed type(16.7％,2/12).All diffuse-type patients exhibited a characteristic cord-like hypoechoic pattern.Cervical lymph node metastasis was observed in all the patients,with 75.0％(9/12)showing lymph nodes＞2 cm in maximum diameter.Thyroid dysfunction occurred in 66.7％(8/12)of patients,including 2 patients with dynamic shifts from hyperthyroidism to hypot-hyroidism.Diffuse and mixed types were associated with hypothyroidism(P=0.038).Conclusions SSCC-T demonstrates specific ultrasonographic features,particularly the cord-like hypoechoic pattern in the diffuse type.For patients with squamous cell carcinoma,regular ultrasound examinations of the thyroid and cervical lymph nodes combined with changes in thyroid function are conducive to the timely detection of thyroid metastasis of squamous cell carcinoma.关键词
继发性甲状腺鳞状细胞癌/甲状腺功能/超声Key words
secondary squamous cell carcinoma of the thyroid/thyroid function/ultrasound分类
医药卫生引用本文复制引用
刘冬,苟砚佳,温泉,宗素婷..继发性甲状腺鳞状细胞癌的超声特征[J].中国医学科学院学报,2025,47(3):390-395,6.基金项目
国家自然科学基金(82001819) （82001819）
