中国医学装备2025，Vol.22Issue(7)：16-20,5.DOI:10.3969/j.issn.1672-8270.2025.07.003
CT评估冠状动脉周围脂肪衰减指数对老年冠心病患者PCI术后再狭窄的预测价值
Predictive value of pericoronary FAI of CT assessment for restenosis post PCI surgery in elderly patients with CHD
摘要
Abstract
Objective:To explore predictive value of pericoronary fat attenuation index(FAI)of the assessment of computed tomography(CT)for coronary restenosis post the surgery of percutaneous coronary intervention(PCI)in elderly patients with coronary heart disease(CHD).Methods:A total of 100 elderly patients with CHD who admitted to Harbin 242 Hospital and underwent PCI from August 2021 to August 2024 were prospectively selected,and they were divided into stenosis group(46 cases)and non-stenosis group(54 cases)based on whether occurred coronary artery restenosis after the surgery.Multivariate logistic regression was used to analyze the influence factors of occurring restenosis in elderly patients with CHD after PCI surgery,and the receiver operating characteristic(ROC)curve was drawn to analyze the predictive value of FAI for restenosis post PCI surgery in patients with CHD.Results:The differences in lipoprotein a,fibrinogen(FIB),total bilirubin(TBIL),total cholesterol(TC),triglyceride(TG),Coronary artery Lesion Complexity Scoring System(SYNTAX)score and FAI were significant between the stenosis group and the non-stenosis group,and the differences were all statistically significant(t=11.819,27.088,38.363,2.632,4.106,7.773,3.231,P<0.05).There were no statistically significant difference in gender,age,body mass index(BMI),blood pressure,basically medical history,and the diameter of implanted stents between the two groups(P>0.05).Multivariate logistic regression analysis showed that lipoprotein a FIB TBIL,TC,TG,SYNTAX score,and FAI index were all influence factors for restenosis post PCI surgery in patients with CHD[OR=4.578(95%CI:2.645～7.932),3.850(95%CI:2.048～7.237),0.145(95%CI:0.052～0.405),6.133(95%CI:1.382～27.219),0.019(95%CI:0.002～0.158),1.264(95%CI:1.150～1.389),1.062(95%CI:1.024～1.102),P<0.05].The ROC curve analysis showed that the area under curve(AUC)value of the ROC curve of the FAI index was 0.760(95%CI:0.666～0.854)in predicting restenosis post PCI surgery,and the sensitivity,specificity,the maximum Youden index and the best cut-off value of that were respectively 89.1%,59.3%,0.484,-79.79,P<0.001.Conclusion:FAI has significant value in predicting restenosis post PCI surgery in elderly patients with CHD,and it can be used as basis of assessing clinical risk.关键词
冠心病/经皮冠状动脉介入治疗(PCI)/脂肪衰减指数(FAI)/老年/冠状动脉狭窄Key words
Coronary heart disease(CHD)/Percutaneous coronary intervention(PCI)/Fat attenuation index(FAI)/Elderly/Coronary artery stenosis分类
医药卫生引用本文复制引用
杨竟博,邹书斌,王晶晶,王锋..CT评估冠状动脉周围脂肪衰减指数对老年冠心病患者PCI术后再狭窄的预测价值[J].中国医学装备,2025,22(7):16-20,5.基金项目
国家自然科学基金(81500377)National Natural Science Foundation of China(81500377) （81500377）
