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Peutz-Jeghers综合征女性患者伴发宫颈胃型腺癌的影像学分析

孟利民 李白容 郑吉春 贾静辉 李相生 王东

中国医学装备2025,Vol.22Issue(7):45-49,5.
中国医学装备2025,Vol.22Issue(7):45-49,5.DOI:10.3969/j.issn.1672-8270.2025.07.009

Peutz-Jeghers综合征女性患者伴发宫颈胃型腺癌的影像学分析

Imaging analysis of concomitant G-EAC in female patients with PJS

孟利民 1李白容 2郑吉春 3贾静辉 4李相生 1王东1

作者信息

  • 1. 空军军医大学空军特色医学中心医学影像科 北京 100142
  • 2. 空军军医大学空军特色医学中心消化内科 北京 100142
  • 3. 空军军医大学空军特色医学中心病理科 北京 100142
  • 4. 空军军医大学空军特色医学中心妇产科 北京 100142
  • 折叠

摘要

Abstract

Objective:To explore the clinical and imaging features of the concomitant gastric-type endocervical adenocarcinoma(G-EAC)in female patients with Peutz-Jeghers syndrome(PJS),so as to improve the early diagnostic level for PJS.Methods:A retrospective analysis was performed on the clinical and imaging data of 12 patients who were confirmed as PJS with G-EAC at Air Force Medical Center,PLA from June 2021 to December 2024.The 12 patients all received computed tomography(CT)examination before surgery,and 6 cases among of them received magnetic resonance imaging(MRI)examination at the same time.The features of clinical performance,and imaging features of CT and MR in all patients were analyzed.Results:In 12 G-EAC patients,7 cases(58.3%)did not occurred any abnormally relative symptoms of gynaecology and obstetrics,while 5 cases(41.7%)occurred increase of vaginal drainage and/or vaginal bleeding.The results of imaging examination indicated that 12 cases occurred concomitant cyst,including 5 cases(41.7%)with large cysts,6 cases(50.0%)that micro cysts coexisted with large cysts,1 case(8.3%)that solid mass combined with small amount of micro cysts,and 4 cases(33.3%)that combined with small amount of uterine cavity effusion.MR performance was the most of occurrences were quasi-circular object with long T1/T2 signals,and the sequences of diffusion weighted imaging(DWI)appeared there was no diffusion or mild restriction,and apparent diffusion coefficient(ADC)appeared slightly high signal.The tumors that mainly were solid components appeared longer T2 signals,which diffusion was limited,and which ADC values appeared low signals.CT images of them presented enlarged cervixes,and mixed-density cystic and solid nodules and mass shadows at local tissues,and cellular change at local lesions.There was not significant strengthen at the cystic fields of the lesion with enhanced scan,and the solid fields appeared uneven enhancement.The accuracy rates both of preoperative CT and MR diagnosis were 50.0%.Conclusion:The clinical appearance,and imaging futures of CT and MR examinations of PJS female patients with G-EAC are respectively:partial patients occur vaginal drainage and/or vaginal bleeding,the most of tumors often occurs at the entire cervix(includes upper segment),often combines with cystic changes,and often appears infiltrating growth.The clinical PJS appearance,CT and MR examinations contribute to early diagnosis for G-EAC.

关键词

黑斑息肉综合征(PJS)/宫颈肿瘤/胃型腺癌/磁共振成像(MRI)/X射线计算机体层扫描(CT)

Key words

Peutz-Jeghers syndrome(PJS)/Uterine cervical neoplasm/Gastric-type endocervical adenocarcinoma(G-EAC)/Magnetic resonance imaging(MRI)/Computed tomography(CT)

分类

医药卫生

引用本文复制引用

孟利民,李白容,郑吉春,贾静辉,李相生,王东..Peutz-Jeghers综合征女性患者伴发宫颈胃型腺癌的影像学分析[J].中国医学装备,2025,22(7):45-49,5.

中国医学装备

1672-8270

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