中华中医药杂志2025，Vol.40Issue(5)：2129-2134,6.
基于联合模型评价中医药治疗艾滋病长期疗效
Evaluation of the long-term efficacy of traditional Chinese medicine in treating AIDS based on joint model
摘要
Abstract
Objective:To analyze the influencing factors of traditional Chinese medicine(TCM)efficacy in AIDS using a joint model,aiming to provide evidence for the long-term clinical effectiveness of TCM in HIV/AIDS treatment.Methods:A 15-year retrospective cohort study was designed using data from the 'HIV/AIDS Comprehensive Prevention and Treatment Data Information System' and the 'TCM Treatment for HIV/AIDS Project Database'.A joint model was constructed to analyze factors influencing TCM efficacy and evaluate its therapeutic outcomes.Results:This study included 2 078 AIDS patients.The joint model analysis demonstrated a statistically significant coefficient of 76.08(P＜0.05)for the TCM intervention group in longitudinal modeling,indicating a therapeutic association with increased CD4+T lymphocyte counts by 76.08 cells/μL compared to control groups.Conclusion:TCM treatment for AIDS not only reduces patient mortality but also enhances CD4+T lymphocyte count,providing valid evidence for the widespread recognition of the long-term clinical effectiveness of TCM in AIDS treatment.关键词
艾滋病/中医药/死亡/联合模型/CD4+T淋巴细胞计数Key words
Acquired immune deficiency syndrome(AIDS)/Traditional Chinese medicine/Death/Joint model/CD4+T lymphocyte count引用本文复制引用
贾皇超,刘学伟,李鹏宇,金艳涛,朱柯颖,姜琦,郭会军..基于联合模型评价中医药治疗艾滋病长期疗效[J].中华中医药杂志,2025,40(5):2129-2134,6.基金项目
国家自然科学基金项目(No.81873187),河南省自然科学基金项目(No.252300421627),郑州市医疗卫生领域科技创新指导计划项目(No.2024YLZDJH060),河南省中医药科学研究专项课题项目(No.2024ZXZX1172,No.2024ZY2034),河南省博士后科研项目(No.HN2024106) （No.81873187）
