中国真菌学杂志2025，Vol.20Issue(3)：251-255,5.
68例儿童侵袭性肺部真菌感染的流行病学特征及影响因素分析
Epidemiological characteristics and influencing factors of invasive pulmonary fungal infections in 68 children
祁军平 1任红 1李玲玲 1张文丽 2黄喜凤 2席飞燕 3安瑰 1尤弘霞1
作者信息
- 1. 兰州市肺科医院呼吸一科,兰州 730046
- 2. 兰州市肺科医院呼吸二科,兰州 730046
- 3. 兰州市肺科医院医务科,兰州 730046
- 折叠
摘要
Abstract
Objective To investigate the epidemiological characteristics and influencing factors of invasive pulmonary fungal infections(IPFIs)in 68 pediatric cases,with the aim of raising clinical awareness and providing a scientific reference for pre-vention,treatment,and reduction of mortality associated with the disease.Method A total of 68 children diagnosed with IPFI were retrospectively analyzed.Data including demographic information,clinical manifestations,microbiological find-ings,and imaging features were collected.Statistical analysis was performed to summarize the epidemiological profile and explore potential risk factors.Results Among the 68 cases,40 were male and 28 female.The most common clinical symp-tom was cough,followed by fever and expectoration.Moist rales were the predominant physical sign.A total of 73 fungal strains were isolated from the respiratory tracts of the 68 patients.The top three pathogens were Candida albicans(43 strains,58.90％),Candida parapsilosis(8 strains,10.96％),and Candida glabrata(7 strains,9.59％).IPFIs were predominantly observed in children with prolonged use of antibiotics,central venous catheterization,invasive mechanical ven-tilation,and parenteral nutrition.Conclusion Invasive pulmonary fungal infections in children are more common in newbo-rns,with Candida albicans as the main pathogen.The main clinical symptoms are non-specific,and there are differences in underlying diseases and invasive factors among different age groups.关键词
儿童/病原学检查/侵袭性肺部真菌感染/流行病学特征/影响因素Key words
children/microbiological findings/invasive pulmonary fungal infection/epidemiological characteristics/influ-ence factor分类
医药卫生引用本文复制引用
祁军平,任红,李玲玲,张文丽,黄喜凤,席飞燕,安瑰,尤弘霞..68例儿童侵袭性肺部真菌感染的流行病学特征及影响因素分析[J].中国真菌学杂志,2025,20(3):251-255,5.
