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Vascular Protection of Neferine on Attenuating Angiotensin Ⅱ-Induced Blood Pressure Elevation by Integrated Network Pharmacology Analysis and RNA-Sequencing Approach

SHEN A-ling CHEN Ke-ji ZHANG Xiu-li GUO Zhi WU Mei-zhu CHENG Ying LIAN Da-wei FU Chang-geng PENG Jun YU Min

中国结合医学杂志（英文版）2025，Vol.31Issue(8)：694-706,13.
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中国结合医学杂志（英文版）2025，Vol.31Issue(8)：694-706,13.DOI:10.1007/s11655-025-4015-6

Vascular Protection of Neferine on Attenuating Angiotensin Ⅱ-Induced Blood Pressure Elevation by Integrated Network Pharmacology Analysis and RNA-Sequencing Approach

Vascular Protection of Neferine on Attenuating Angiotensin Ⅱ-Induced Blood Pressure Elevation by Integrated Network Pharmacology Analysis and RNA-Sequencing Approach

SHEN A-ling 1CHEN Ke-ji 1ZHANG Xiu-li 2GUO Zhi 2WU Mei-zhu 2CHENG Ying 2LIAN Da-wei 2FU Chang-geng 3PENG Jun 2YU Min4

作者信息

  • 1. Department of Cardiology,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing(100091),China||National Clinical Research Center for Cardiovascular Diseases of Traditional Chinese Medicine,Beijing(100091),China||Postdoctoral Workstation,Tianjiang Pharmaceutical Co.,Ltd.,Jiangyin,Jiangsu Province(214400),China||Academy of Integrative Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou(350122),China||Fujian Key Laboratory of Integrative Medicine on Geriatrics,Fujian University of Traditional Chinese Medicine,Fuzhou(350122),China||Fujian Collaborative Innovation Center for Integrative Medicine in Prevention and Treatment of Major Chronic Cardiovascular Diseases,Fuzhou(350122),China
  • 2. Academy of Integrative Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou(350122),China||Fujian Key Laboratory of Integrative Medicine on Geriatrics,Fujian University of Traditional Chinese Medicine,Fuzhou(350122),China||Fujian Collaborative Innovation Center for Integrative Medicine in Prevention and Treatment of Major Chronic Cardiovascular Diseases,Fuzhou(350122),China
  • 3. Department of Cardiology,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing(100091),China||National Clinical Research Center for Cardiovascular Diseases of Traditional Chinese Medicine,Beijing(100091),China||Academy of Integrative Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou(350122),China||Fujian Key Laboratory of Integrative Medicine on Geriatrics,Fujian University of Traditional Chinese Medicine,Fuzhou(350122),China||Fujian Collaborative Innovation Center for Integrative Medicine in Prevention and Treatment of Major Chronic Cardiovascular Diseases,Fuzhou(350122),China
  • 4. Postdoctoral Workstation,Tianjiang Pharmaceutical Co.,Ltd.,Jiangyin,Jiangsu Province(214400),China
  • 折叠

摘要

关键词

neferine/hypertension/vascular contraction/calcium/extracellular signal-regulated kinase 1/2/Chinese medicine

Key words

neferine/hypertension/vascular contraction/calcium/extracellular signal-regulated kinase 1/2/Chinese medicine

引用本文复制引用

SHEN A-ling,CHEN Ke-ji,ZHANG Xiu-li,GUO Zhi,WU Mei-zhu,CHENG Ying,LIAN Da-wei,FU Chang-geng,PENG Jun,YU Min..Vascular Protection of Neferine on Attenuating Angiotensin Ⅱ-Induced Blood Pressure Elevation by Integrated Network Pharmacology Analysis and RNA-Sequencing Approach[J].中国结合医学杂志（英文版）,2025,31(8):694-706,13.

基金项目

Suppported by the National Natural Science Foundation of China(No.82074363 and No.U22A20372),the Scientific Research Foundation for the Top Youth Talents of Fujian University of Traditional Chinese Medicine(No.XQB202202),the Development Fund of CHEN Ke-ji Integrative Medicine(No.CKJ2020003),Scientific Research Foundation for the High Level Talents,Fujian University of Traditional Chinese Medicine(No.X2020004-talents),and Fujian Research and Training Grants for Young and Middle-aged Leaders in Healthcare （No.82074363 and No.U22A20372）

中国结合医学杂志（英文版）

1672-0415

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