中国卒中杂志2025,Vol.20Issue(6):657-662,6.DOI:10.3969/j.issn.1673-5765.2025.06.001
脑血管病的多组学研究
Multi-omics Research in Cerebrovascular Disease
摘要
Abstract
Currently,cerebrovascular disease still faces challenges in elucidating mechanisms,constructing specialized cohorts,and developing new drugs.The advancement of multi-omics has provided a driving force for understanding the complex pathophysiological regulatory mechanisms,optimizing disease classification and diagnosis,enhancing prognosis prediction capabilities,and advancing the new drug development process.China has established the STROMICS database,a multi-omics and multimodal database of cerebrovascular disease at the ten-thousand-person level.China will further develop a more comprehensive multi-omics cohort for cerebrovascular disease and advance multi-omics research through interdisciplinary approaches such as Mendelian randomization.This will provide methods to deepen the understanding of the regulatory mechanisms underlying cerebrovascular disease and to facilitate new drug development.关键词
脑血管病/卒中/多组学Key words
Cerebrovascular disease/Stroke/Multi-omics分类
医药卫生引用本文复制引用
张杰,李昊,程丝..脑血管病的多组学研究[J].中国卒中杂志,2025,20(6):657-662,6.基金项目
国家自然科学基金(82471304)国家重点研发计划(2022YFE0209600)中国科协青年人才托举工程(2023QNRC001) (82471304)