中国卒中杂志2025，Vol.20Issue(7)：829-839,11.DOI:10.3969/j.issn.1673-5765.2025.07.005
急性缺血性卒中超早期血压管理研究进展
Research Progress on Ultra-Early Blood Pressure Management in Acute Ischemic Stroke
摘要
Abstract
Stroke is one of the leading causes of disability and death worldwide,with ischemic stroke accounting for over 70％of all stroke cases,making it a major global public health issue.Patients with acute ischemic stroke(AIS)often exhibit elevated blood pressure in the early phase after onset,and numerous observational studies suggest that elevated blood pressure is associated with poor prognosis.The core challenge in ultra-early blood pressure management for AIS lies in the dual-directional impact of blood pressure fluctuations on the ischemic penumbra against the backdrop of impaired cerebral autoregulation.A rational blood pressure management strategy is one of the key factors to improve patient outcomes.Currently,significant controversies persist regarding the timing of blood pressure lowering,individualized blood pressure target setting,and the effects of different antihypertensive strategies on cerebral perfusion and reperfusion injury in the ultra-early phase of AIS.Given this,this article reviews and discusses the latest research progress in ultra-early blood pressure management for AIS,aiming to provide more valuable references for clinical practice.关键词
急性缺血性卒中/超早期/血压管理/缺血再灌注损伤Key words
Acute ischemic stroke/Ultra-early phase/Blood pressure management/Ischemia reperfusion injury分类
医药卫生引用本文复制引用
杨志进,谭荃丹,毛凤凯,李朝晖,陈晨,李刚,杨杰,林亚鹏..急性缺血性卒中超早期血压管理研究进展[J].中国卒中杂志,2025,20(7):829-839,11.基金项目
国家自然科学基金面上项目(82171295)四川省科技计划项目重点研发计划(2023YFS0042) （82171295）
