转化医学杂志2025，Vol.14Issue(6)：36-40,5.DOI:10.3639/j.issn.2095-3097.2025.06.007
不同液体复苏方式对多发伤伴低血容量性休克患者治疗效果的影响
The Influence of Different Fluid Resuscitation Methods on The Therapeutic Effect of Patients with Multiple Injuries Accompanied by Hypovolemic Shock
摘要
Abstract
Objective To compare the effect of limited fluid resuscitation or conventional adequate fluid resuscitation on patients with multiple trauma and hypovolemic shock.Methods Eighty patients with multiple trauma complicated by hy-povolemic shock admitted to 901st Hospital,Joint Logistic Support Force of PLA were selected from March 2021 to March 2024,and were divided into two groups according to the time of admission.The control group(n=40)was treated with conventional adequate fluid resuscitation,while the observation group(n=40)received limited fluid resuscitation.The following were com-pared between groups:oxygen metabolism indicators[blood lactic acid(BLA),arterial oxygen partial pressure(PaO2),oxygen-ation index(OI)],coagulation function[prothrombin time(PT),activated partial thromboplastin time(APTT)],hemoglobin(Hb),hematocrit(HCT),urine volume,complications and mortality.Results In the observation group and the control group,3 cases and 5 cases died within 24h after resuscitation,and 1 case and 3 cases died from resuscitation to discharge,respectively.There was no significant difference in mortality between the two groups(P>0.05).After resuscitation,BLA decreased in both groups(P<0.05).PaO2 and OI in the observation group were increased(P<0.05),while PaO2 and OI were decreased in the control group(P<0.05).Furthermore,BLA in the observation group was lower than in the control group(P<0.05),and PaO2 and OI were higher than in the control group(P<0.05).PT and APTT in both groups were prolonged after resuscitation(P<0.05),and PT and APTT were shorter in the observation group than in the control group(P<0.05).After resuscitation,Hb and HCT decreased in both groups(P<0.05)while urine volume increased(P<0.05).Hb and HCT in the observation group were higher than in the control group(P<0.05),but there was no significant difference in urine volume compared with that in the control group(P>0.05).The total incidence of complications in the observation group was 17.50%,which was not statistically significant compared with that in the control group(32.50%)(P>0.05).Conclusion Compared with conventional adequate fluid resuscitation,limited fluid resuscitation is more conducive to stabilizing clinical indicators such as oxygen metabolism and coagulation function indicators,Hb,and HCT,and promoting early recovery in patients with multiple trauma complicated by hypovolemic shock.关键词
多发伤/低血容量性休克/限制性液体复苏/充分液体复苏Key words
Multiple trauma/Hypovolemic shock/Limited fluid resuscitation/Adequate fluid resuscitation分类
医药卫生引用本文复制引用
苏令,朱灿,李俊,王李,章福彬..不同液体复苏方式对多发伤伴低血容量性休克患者治疗效果的影响[J].转化医学杂志,2025,14(6):36-40,5.基金项目
安徽省卫生健康软科学研究项目(2020WR03003) （2020WR03003）
