浙江大学学报（医学版）2025，Vol.54Issue(3)：281-288,8.DOI:10.3724/zdxbyxb-2024-0585
全球子宫颈癌疾病负担及子宫颈癌筛查与管理质量分析
Global disease burden of cervical cancer and the association of screening coverage with quality of disease management
摘要
Abstract
Objective:To analyze the global disease burden of cervical cancer and the association between screening coverage and the quality of disease management.Methods:The data of global burden of cervical cancer 2021 and the data of cervical cancer screening 2019 were obtained from IHME Global Burden of Disease(GBD)and the WHO global health observatory,respectively.The age-standardized disease burden index was calculated,the quality of care index(QCI)was determined with principal component analysis,and the correlation between QCI and cervical cancer screening coverage was examined with linear regression analysis by regions and populations.Results:The burden of cervical cancer and the quality of management exhibited significant variability across countries with differing levels of social development.The indicators of cervical cancer burden in China were close to the average level of countries with higher socio-demographic index(SDI).The global QCI was 22.22(10.50,35.43),and that of China was 26.30.The global screening coverage rate for cervical cancer was 42％(12％,86％)and that in China was 31％.After adjusting for the social development level of countries,the coverage level of cervical cancer screening was associated with QCI(β=0.27,P＜0.01),with no difference between low and high SDI countries(P＞0.05).The association was significantly stronger among 25-30 years old women(β=1.48,P＜0.05).Conclusions:There are discrepancies in both the disease burden of cervical cancer and the quality of disease management among countries with different socioeconomic levels,and there is still considerable room for improvement in China.Expanding coverage of cervical cancer screening may be an effective strategy to enhance the management quality of cervical cancer,particularly among younger women where the screening benefits are most pronounced.关键词
子宫颈癌/疾病负担/管理质量指数/子宫颈癌筛查/社会人口指数Key words
Cervical cancer/Burden of disease/Quality of care index/Cervical cancer screening/Socio-demographic index分类
医药卫生引用本文复制引用
孙畅,MUSTAFE Abdalle Abdi,刘冰青,马袁英,吕卫国..全球子宫颈癌疾病负担及子宫颈癌筛查与管理质量分析[J].浙江大学学报（医学版）,2025,54(3):281-288,8.基金项目
浙江省公益技术应用研究(LGF22H260007) （LGF22H260007）
国家自然科学基金(72204215) The study was supported by the Public Welfare Technology Application Research of Zhejiang Province(LGF22H260007)and National Natural Science Foundation of China(72204215) （72204215）
