神经药理学报2025，Vol.15Issue(2)：20-24,5.DOI:10.3969/j.issn.2095-1396.2025.02.004
不同剂量喷他佐辛用于无痛胃镜检查术的效果观察
Observation of the Effect of Different Doses of Pentazocin for Painless Gastroscopy
李慧 1韩雷 1袁莉2
作者信息
- 1. 北京中西医结合医院麻醉科,北京,100039,中国
- 2. 河北北方学院附属第一医院麻醉科,张家口,075000,中国
- 折叠
摘要
Abstract
Objective:To explore the effect of different doses of pentazocine in painless gastroscopy.Methods:A total of 200 patients who underwent painless gastroscopy in the First Affiliated Hospital of Hebei North University from January 2022～January 2023 were selected.All patients were divided into four groups:group A(pentazocin 0.2 mg·kg-1),group B(pentazocine 0.5 mg·kg-1),group C(pentazocine 0.8 mg·kg-1)and group D(control group:sufentanil 0.08 ug·kg-1),with 50 cases in each group.Observation indicators:The behavioural pain scale non-infused(BPS-NI)score was used to compare the analgesic effect of the four groups.The mean arterial pressure(MAP)pressure and heart rate(HR)of the four groups were compared before operation(T0),gastroscopy across the glottis to the upper esophageal end(T1),and at the time of awakening(T2),and the recovery time,recovery ventricular retention time and total amount of propofol were recorded.The occurrence of intraoperative and postoperative adverse reactions was compared.Results:Compared with group D(control group),group A had worse analgesic effect(P<0.05),and the dosage,recovery time and retention time of PACU were higher than those in group D.The dosage of propofol in group C was lower than that in group D,but the recovery time and retention time and incidence of adverse reactions in group C were significantly higher than those in group C(P>0.05).The BPS-NI score and analgesic success rate of group B were similar to those of group D(P>0.05),but the incidence of postoperative adverse reactions was lower than that of group D,and the hemodynamic stability was better than that of group D.Conclusion:Pentazocine at 0.5 mg·kg-1 has the best effect in painless gastrointestinal endoscopy,which is worthy of clinical promotion.关键词
喷他佐辛/不同剂量/无痛胃镜/效果观察Key words
pentazocine/different doses/painless gastroscopy/effect observation分类
医药卫生引用本文复制引用
李慧,韩雷,袁莉..不同剂量喷他佐辛用于无痛胃镜检查术的效果观察[J].神经药理学报,2025,15(2):20-24,5.
