浙江中医药大学学报2025，Vol.49Issue(6)：674-683,10.DOI:10.16466/j.issn1005-5509.2025.06.002
卵巢功能减退患者相关经穴红外热辐射特性规律分析
Study on Infrared Thermal Characteristics of Meridian Points for Diminished Ovarian Reserve
摘要
Abstract
[Objective]To discover the changes in the thermal characteristics of meridian points in patients with diminished ovarian reserve(DOR)under pathological conditions,and to filter possible optimal acupoints for diagnosis of DOR.[Methods]There was a cross-sectional survey with 50 DOR patients and 50 healthy participants included,to detect the infrared thermal characteristics of certain acupoints,by observing the skin temperature and regional local temperature of 27 certain acupoints that were used to diagnose and treat DOR.The relative temperature was the acupoint's temperature minus regional local temperature.Calculate the relative temperature of acupoints and compare the difference between two groups.Logistic regression analysis of acupoints that showed significant difference were used to examine whether DOR related acupoint temperature was the risk of DOR in women.Prediction model for increased DOR risk was constructed and evaluated by using the receiver operating characteristic curve(ROC)and the area under curve(AUC).Using Spearman's test to analyze the correlation between the temperature of DOR-related and modified Kupperman Index(KI).[Results]Comparing with control group,the relative temperature of Zhongwan(CV12),Guanyuan(CV4),Qixue(KI13),right Siman(KI14)and right Shangliao(BL31)showed a significant decrease in DOR patients(P<0.05).Right Shangliao(BL31)was significantly negatively correlated with KI(P<0.05).According to the results of binary logistic regression,the relative temperatures of Zhongwan(CV12),right Siman(KI14)and right Shangliao(BL31)were closely bound up with DOR risk(P<0.05).The ROC curve was constructed basing on the temperature of the above three acupoints and the AUC of the prediction model was 0.775.[Conclusion]The acupoints related to DOR exhibit specific thermal radiation changes,demonstrating potential predictive value as an auxiliary diagnostic tool for DOR risk.关键词
卵巢功能减退/红外热辐射/经穴特异性/早期诊断/体表温度/经穴温度/经络脏腑相关/腧穴敏化Key words
diminished ovarian reserve/infrared thermography/acupoint specificity/early diagnosis/body surface temperature/acupoint's temperature/meridian-viscera correlation/acupoint sensitization分类
医药卫生引用本文复制引用
刘涵予,邵晓梅,孙颢珉,陈思淇,黄美,张雅俊,郦沛祺,马景,陈勤,方剑乔..卵巢功能减退患者相关经穴红外热辐射特性规律分析[J].浙江中医药大学学报,2025,49(6):674-683,10.基金项目
国家重点研发计划"中医药现代化"重点专项课题(2022YFC350401) National Key Research and Development Program"Modernization of Traditional Chinese Medicine"Key Special Project(2022YFC350401) （2022YFC350401）
