肿瘤防治研究2025，Vol.52Issue(7)：539-547,9.DOI:10.3971/j.issn.1000-8578.2025.24.1051
消化道肿瘤中免疫检查点药物治疗瓶颈的思考
Bottlenecks of Immune Checkpoint Inhibitors in Treatment of Gastrointestinal Tumors
韩春 1白莉2
作者信息
- 1. 102600 北京,北京美中爱瑞肿瘤医院日间化疗中心
- 2. 100853 北京,解放军总医院第一医学中心肿瘤内科
- 折叠
摘要
Abstract
Immune checkpoint inhibitors(ICIs),as one of relatively advanced antitumor treatment methods in recent years,have achieved significant therapeutic effects in the treatment of multiple systemic tumors.However,their application in gastrointestinal tumors is not satisfactory,with treatment bottlenecks.This article summarizes the challenges and possible solutions faced by ICIs in the treatment of gastrointestinal tumors to help clinicians better understand the limitations and future development directions of ICIs and thus develop more effective treatment strategies.关键词
免疫检查点抑制剂/消化道肿瘤/肿瘤微环境/炎性反应/肠道菌群Key words
ICIs/Gastrointestinal tumors/Tumor microenvironment(TME)/Inflammation/Gut microbiota分类
医药卫生引用本文复制引用
韩春,白莉..消化道肿瘤中免疫检查点药物治疗瓶颈的思考[J].肿瘤防治研究,2025,52(7):539-547,9.
