中国现代医生2025，Vol.63Issue(19)：42-45,50,5.DOI:10.3969/j.issn.1673-9701.2025.19.009
2型糖尿病患者视网膜血管直径与LDL-C的相关性研究
Study on the correlation between retinal vascular diameter and LDL-C in patients with type 2 diabetes mellitus
林丽丽 1许景芬 1叶荣洲 1李秀研 1李骞1
作者信息
- 1. 福建医科大学附属泉州第一医院全科医学科,福建泉州 362000
- 折叠
摘要
Abstract
Objective To explore the effect of low density lipoprotein-cholesterol(LDL-C)on the diameters of retinal arteries and veins in patients with type 2 diabetes mellitus(T2DM).Methods A total of 102 patients with T2DM who treated in Quanzhou First Hospital Affiliated to Fujian Medical University from January to September 2024 were selected and divided into Group A(LDL-C＜2.6mmol/L,35 cases),Group B(2.6mmol/L≤LDL-C＜3.4mmol/L,33 cases)and Group C(LDL-C≥3.4mmol/L,34 cases)according to the LDL-C level.The clinical data and color fundus photos of the patients were collected.The superior temporal retinal arteriolar equivalent(RAE)and superior temporal retinal venular equivalent(RVE)in the left eye of patients were measured,and the ratio of arteriovenous diameters(AVR)was calculated.The correlation between LDL-C levels and retinal vascular diameters was analyzed.Results There were statistically significant differences in levels of total cholesterol and triglycerides,as well as the proportions of patients with coronary heart disease and diabetic retinopathy(DR)among the three groups(P＜0.05).With the progression of DR,the level of LDL-C gradually increases(P＜0.05).There were statistically significant differences in RAE and AVR among patients with different DR stages(P＜0.05).There were statistically significant differences in RAE and AVR among three groups of patients(P＜0.05).Correlation analysis showed that RAE and AVR were negatively correlated with LDL-C(P＜0.05).Conclusion With the increase of LDL-C level,the degree of DR aggravates,and RAE and AVR decrease accordingly.However,there is no significant correlation between LDL-C and RVE.关键词
糖尿病性视网膜病变/低密度脂蛋白胆固醇/视网膜血管直径Key words
Diabetic retinopathy/Low density lipoprotein-cholesterol/Retinal vascular diameter分类
医药卫生引用本文复制引用
林丽丽,许景芬,叶荣洲,李秀研,李骞..2型糖尿病患者视网膜血管直径与LDL-C的相关性研究[J].中国现代医生,2025,63(19):42-45,50,5.
