遵义医科大学学报2025,Vol.48Issue(7):713-718,6.
CT评分联合血常规指标预测重症急性胰腺炎住院死亡风险分析
CT score combined with blood routine indexes to predict hospitalized death in severe acute pancreatitis
摘要
Abstract
Objective To assess the predictive value of modified CT severity index(MCTSI)score combined with blood routine indexes for death during hospitalization in patients with severe acute pancreatitis(SAP).Methods A total of 338 SAP patients hospitalized in our hospital from January 2021 to December 2024 were ret-rospectively included,which were divided into 80 cases(23.67%)in the in-hospital death group and 258 cases(76.33%)in the in-hospital survival group according to the prognosis during hospitalization.Factors influencing death during hospitalization in SAP patients were screened by logistic regression analysis,and the predictive value of MCTSI score combined with routine blood parameters was assessed by ROC curve.Results Univariate analysis showed that age,MCTSI score,Ranson score,red blood cell distribution width(RDW),mean platelet volume(MPV),and neutrophil-lymphocyte ratio(NLR)were significantly higher in the in-hospital death group com-pared with the in-hospital survival group(P<0.05).Multifactorial logistic regression analysis showed that MCT-SI score(OR=2.314,95%CI:1.631-3.283),Ranson score(OR=1.844,95%CI:1.332-2.552),MPV(OR=1.507,95%CI:1.140-1.991),NLR(OR=1.788,95%CI:1.289-2.480)were risk factors for death during hospitalization in SAP patients.The ROC curves showed that the AUCs of single indexes(MCTSI score,Ranson score,MPV,and NLR)for the prediction of death during hospitalization in SAP patients ranged from 0.626-0.734,respectively,whereas the MCTSI score in combination with the NLR and the MPV had the best predictive efficacy(AUC=0.945,sensitivity 88.75%,specificity 87.98%).Conclusion MCTSI score com-bined with routine blood parameters can effectively predict the risk of death during hospitalization in SAP pa-tients,and its combined model has the highest predictive value.关键词
重症急性胰腺炎/改良CT严重指数/平均血小板体积/中性粒细胞淋巴细胞比值Key words
severe acute pancreatitis/modified CT severity index/mean platelet volume/neutrophil lympho-cyte ratio分类
医药卫生引用本文复制引用
李安琪,董仲魁,韩瑜,牛思佳..CT评分联合血常规指标预测重症急性胰腺炎住院死亡风险分析[J].遵义医科大学学报,2025,48(7):713-718,6.基金项目
黑龙江省自然科学基金资助项目(NO:H2020L038). (NO:H2020L038)