法医学杂志2025，Vol.41Issue(2)：111-119,9.DOI:10.12116/j.issn.1004-5619.2024.440206
米酵菌酸中毒的法医学研究进展
Forensic Research Progress on Bongkrekic Acid Poisoning
摘要
Abstract
Bongkrekic acid(BA)is a toxin with stable properties and no distinctive smell.It exists in common foods such as fermented edible grain products,potato products,spoiled tremella fuciformis and auricularia polytricha,as well as auricularia polytricha that has been soaked too long.It can easily cause food poisoning.At present,there is still a lack of complete method to detect BA,and no spe-cific antidote of BA has been found.Therefore,BA poisoning is easy to be misdiagnosed or missed diagnosed,and its mortality rate remains high.In recent years,studies have revealed the toxic mecha-nism of BA and found that BA can inactivate some enzymes containing thiol groups(-SH)and in-hibit the synthesis and transport of adenosine triphosphate(ATP),causing damage to liver,kidney,brain and other parenchymal organs.This article reviews the autopsy cases and literature of deaths caused by BA poisoning at home and abroad,systematically summarizes the epidemiology,clinical manifestations,pathological changes,toxicological mechanisms,detection methods,forensic diagnostic key points and challenges of BA in forensic medicine,with the aim of providing a reference for foren-sic identification of related cases.关键词
法医病理学/法医毒理学/米酵菌酸/中毒/综述Key words
forensic pathology/forensic toxicology/bongkrekic acid/poisoning/review分类
医药卫生引用本文复制引用
陈轩龙,袁强,孙勇,张碟,伏建斌,李立亮..米酵菌酸中毒的法医学研究进展[J].法医学杂志,2025,41(2):111-119,9.基金项目
国家自然科学基金资助项目(82470265,82322033) （82470265,82322033）
