口腔疾病防治2025，Vol.33Issue(8)：666-671,6.DOI:10.12016/j.issn.2096-1456.202550084
早萌上颌前磨牙慢性根尖周炎再生性牙髓治疗1例及文献回顾
Regenerative endodontic procedures for a prematurely erupted maxillary premolar with immature roots and chronic apical periodontitis:a case report and literature review
摘要
Abstract
Objective To investigate treatment strategies for chronic periapical periodontitis in prematurely erupted premolars and provide guidance for managing pulp and periapical diseases in young permanent teeth with im-mature roots.Methods A regenerative endodontic procedure(REP)was performed on a prematurely erupted maxillary left first premolar(tooth 24)at Nolla stage Ⅶ with chronic apical periodontitis,following standardized protocols includ-ing root canal irrigation,disinfection,and coronal sealing.The case was followed up,and a literature review was con-ducted.Results Clinical resolution of symptoms was observed on tooth 24,with sustained root development.After a 20-month follow-up,the tooth had restored biological function.Literature synthesis revealed that periapical infections in prematurely erupted permanent teeth predominently arise from pulp exposure and bacterial infection,with retrograde in-fection being rare.For young permanent teeth with necrotic pulp,regenerative endodontic procedures has been estab-lished as the treatment of choice to promote apical closure and root maturation.The critical steps of regenerative end-odontic procedures include thorough disinfection,induced bleeding to form a fibrin scaffold,and coronal sealing to fa-cilitate stem cell recruitment and differentiation.Conclusion Regenerative endodontic procedures represents an effec-tive and viable treatment option for prematurely erupted young permanent teeth with chronic periapical periodontitis.关键词
早萌/年轻恒牙/Nolla Ⅶ期/前磨牙/慢性根尖周炎/再生性牙髓治疗/根管消毒/冠方封闭Key words
premature eruption/young permanent teeth/Nolla stage Ⅶ/premolar/chronic periapical peri-odontitis/regenerative endodontic procedures/root canal disinfection/coronal sealing分类
医药卫生引用本文复制引用
王晓,夏商,刘燕,杨玉娥,李红..早萌上颌前磨牙慢性根尖周炎再生性牙髓治疗1例及文献回顾[J].口腔疾病防治,2025,33(8):666-671,6.基金项目
青岛市医疗卫生重点学科建设项目资助(2025-2027) （2025-2027）
青岛市口腔疾病临床医学研究中心(22-3-7-lczx-7-nsh) （22-3-7-lczx-7-nsh）
山东省医药卫生口腔内科学重点学科(青岛大学附属青岛市口腔医院)(2025-2027) This study was supported by the grants from Qingdao Key Health Discipline Development Fund(No.2025-2027) （青岛大学附属青岛市口腔医院）
Qing-dao Clinical Research Center for Oral Diseases(No.22-3-7-lczx-7-nsh) （No.22-3-7-lczx-7-nsh）
Shandong Provincial Key Medical and Health Discipline of Oral Medicine(Qingdao University Affiliated Qingdao Stomatological Hospital)(No.2025-2027). （Qingdao University Affiliated Qingdao Stomatological Hospital）
